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I-Massspectrometry

  • Proteomics

    I-Proteomics

    I-Proteomics ibandakanya ukusetshenziswa kobuchwepheshe bokulinganisa kwawo wonke amaprotheni akhona kuseli, izicubu noma into ephilayo.Ubuchwepheshe obusekelwe ku-Proteomics busetshenziswa ngezindlela ezihlukahlukene ezilungiselelweni ezihlukene zocwaningo njengokutholwa kwezimpawu zokuxilonga ezihlukahlukene, abantu abazoklama imithi yokugoma, ukuqonda izindlela ze-pathogenicity, ukuguqulwa kwamaphethini okukhuluma ngokusabela kumasignali ahlukene kanye nokuchazwa kwezindlela zamaprotheni ezisebenzayo ezifweni ezihlukahlukene.Njengamanje, ubuchwepheshe be-quantitative proteomics buhlukaniswe ikakhulukazi ngamasu e-TMT, Amahhala Elebula kanye ne-DIA.

  • Metabolomics

    I-Metabolomics

    I-metabolome iwumkhiqizo ogcina phansi womfula we-genome futhi iqukethe isamba esiphelele sawo wonke ama-molecule anesisindo esiphansi (ama-metabolite) kuseli, izicubu, noma into ephilayo.I-Metabolomics ihlose ukukala ububanzi obubanzi bama-molecule amancane kumongo wezinto eziphilayo noma izimo zezifo.Izindlela ze-Metabolomics ziwela emaqenjini amabili ahlukene: i-metabolomics engahlosiwe, ukuhlaziya okuhlosiwe okuhlosiwe kwazo zonke izihlaziyi ezingalinganiseka kusampula okuhlanganisa namakhemikhali angaziwa kusetshenziswa i-GC-MS/LC-MS, kanye ne-metabolomics ehlosiwe, ukukalwa kwamaqembu achaziwe aphawulwe ngamakhemikhali kanye ama-metabolites ane-biochemically annotated.

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