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条形 isibhengezo-03

Imikhiqizo

I-GWAS

Ucwaningo lwe-Genome-wide association (GWAS) luhlose ukuhlonza okuhlukile kofuzo (i-genotype) ehlotshaniswa nezici ezithile (i-phenotype).Ucwaningo lwe-GWA luphenya izimpawu zofuzo eziwela lonke i-genome yenani elikhulu labantu futhi zibikezela izinhlangano ze-genotype-phenotype ngokuhlaziywa kwezibalo ezingeni labantu.Ukulandelanisa kabusha kwezakhi zofuzo kungathola zonke izinhlobo zofuzo.Ngokuhambisana nedatha ye-phenotypic, i-GWAS ingacutshungulwa ukuze kuhlonzwe ama-SNP ahlobene ne-phenotype, ama-QTL kanye nezakhi zofuzo zamakhandidethi, okusekela ngokuqinile ukuzalaniswa kwezilwane/izitshalo kwesimanje.I-SLAF isu lokulandelanisa i-genome elenziwe lula, elithola izimpawu ezisatshalaliswe ngofuzo olubanzi, i-SNP.Lawa ma-SNP, njengama-molecular genetic markers, angacutshungulwa ukuze kuhlangatshezwane nezifundo nezici ezihlosiwe.Kuyisu elingabizi kakhulu ekuhlonzeni izici eziyinkimbinkimbi ezihlobene nokuhlukahluka kofuzo.


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Ukugeleza komsebenzi we-Bioinformatics


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  • I-Bioinformatics

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