I-BMKGENE ibonelele ngeenkonzo zolandelelwano lwe-spatial transcriptome kuphononongo "I-STEEL yenza i-high-resolution delineation ye-spatiotemporal transcriptomic data", eyapapashwa kwiiNgcaciso kwi-Bioinformatics.
Olu phononongo lucebise i-algorithm esekelwe kulwazi olungajongwanga noluphindaphindeneyo olusekelwe ekufundeni, i-Spatial Transcriptome cEll typE clustering (STEEL), echonga imimandla esuka kwi-transcriptome yendawo ngokuhlanganisa amaso abonisa zombini iiprofayili zokubonisa imfuza efanayo kakhulu kunye nokuvala umgama wesithuba ngendlela yeegrafu.
Uvavanyo olubanzi lwe-STEEL kwiiseti zedatha ye-transcriptomic yendawo evela kwi-platform ye-Visium ye-10X ibonisa ukuba ayiphumeleli kuphela isisombululo esiphezulu sokubonisa izakhiwo ezintle zobuchopho bemouse kodwa yenza ukuba kudityaniswe izilayidi zezicubu ezininzi ezihlalutyelwe zibe nkulu.
Ngokuqhubela phambili kwetekhnoloji ye-transcriptome yesithuba, indlela yethu iya kuba nokusebenziseka okukhulu ekuchongeni isizinda kunye nokwakhiwa kwakhona kweatlasi yegenesis.
CofaAphaukufunda ngakumbi malunga nesi sifundo.
Ixesha lokuposa: Oct-20-2023