Ka 2021, BMKGENE e bone patlisiso ea 31 De novo genome e phatlalalitsoeng ka katleho likoranteng tse nang le tšusumetso e kholo tse nang le lintlha tse felletseng tse fetang 320. Lingoliloeng tse 15 li ile tsa ngoloa hammoho 4 ea tsona e ngotsoe ka kopanelo e le bangoli ba pele ke BMKGENE.
Hang ka mor'a hore selemo sa 2022 se qale, ho se ho ntse ho e-na le lingoloa tse peli tsa lipatlisiso tse hatisitsoeng koranteng ea "Natural Genetics" le "Molecular Plant" ka ho latellana.Ke, "Li-haplotype tse peli tse fapaneng tse tsoang ho heterozygous lychee genome e phahameng haholo li fana ka maikutlo a liketsahalo tse ikemetseng tsa malapeng bakeng sa mefuta ea pele le ea morao-rao" (Lipatlisiso tsa Lychee genome, tse entsoeng ke College of Horticulture, South China Agricultural university, le bathusi ba saense, e hatisitsoeng ho Natural Genetics. ), le “Tatelano ea Genome ea mefuta e mehlano ea Sitopsis ea Aegilops le tšimoloho ea koro ea polyploid B-subgenome” (Five Sitopsis species genome, e entsoeng ke sehlopha sa lipatlisiso sa Moprofesa Bao Liu sa Northeast Normal University.).Re tla boela re hlahlobe lihlooho tsena tse peli 'me re arolelane le babali ba rona.
Joale, ha re shebeng lingoloa tse ntle haholo tsa lipatlisiso tse hatisitsoeng ka 2021 tse ngotsoeng ke BMK le lits'ebeletso tsa rona tse sebelisaneng.
Genome ea Semela - Katleho ea mefuta e mengata.
1. Kopano ea boleng bo holimo ea genome e totobatsa litšobotsi tsa rye genomic le mefuta ea bohlokoa ea temo.
Setsi se Kopantsoeng: Univesithi ea Temo ea Henan
Journal: Natural Genetics
Tšusumetso: 38.31
Morerong ona, ho ile ha hlophisoa genome ea Weining rye, mofuta oa rye oa China oa maemo a holimo.Li-contigs tse kopaneng (7.74 Gb) li nkile karolo ea 98.47% ea boholo bo hakantsoeng ba genome (7.86 Gb), 'me 93.67% ea li-contigs (7.25 Gb) e abetsoe li-chromosome tse supileng.Lintho tse pheta-phetoang li ne li etsa 90.31% ea genome e kopaneng.Litlhahlobo tse ling tsa kopano ea Weining li fane ka leseli le lecha mabapi le phetiso ea liphatsa tsa lefutso ka bophara le phello ea tsona ho liphatsa tsa lefutso tsa starch biosynthesis, tlhophiso ea 'mele ea prolamin loci e rarahaneng, likarolo tsa liphatsa tsa lefutso tse ka sehloohong le libaka tsa chromosomal tse amanang le ho ruuoa lapeng le loci ho rye.Tatelano ena ea liphatsa tsa lefutso e tšepisa ho potlakisa lithuto tsa genomic le ho ikatisa ho rye le lijalo tse amanang le lijo-thollo.
2.Rose ntle le prickle: lintlha tsa genomic tse amanang le ho ikamahanya le mongobo
Setsi se Kopantsoeng: Setsi sa Botany sa Kunming, Sekolo sa Mahlale sa China
Journal: Tlhahlobo ea Sechaba ea Saense
Ntlha ea Tšusumetso: 17.273
Morerong ona, ho ile ha bokelloa lisampole tsa 'Basye's Thornless' (BT, mofuta oa mofuta oa Rosa wichuraiana), 'Old Blush' (OB, mofuta oa mofuta oa lirosa), mefuta e nyalisitsoeng ea bona ea F1 le BCF1.'Me ho ile ha hlahisoa kopano ea boleng bo holimo ea genome ho khetholla liphatsa tsa lefutso tse amanang le nts'etsopele ea stem prickle.Boholo ba genome bo ka ba 530.6 Mb.Ho netefatsa boleng ba genome e kopaneng, tlhahlobo e kang papiso ea 'mapa oa liphatsa tsa lefutso, BUSCO, NGS e bala hape, ha e bapisoa le OB haplotype, tatellano ea taolo ea phoso ea motheo le tlhahlobo ea boleng ba genome-wide LTR Assembly Index (LAI = 20.03) e ile ea etsoa.Patlisiso ena e senola mokhoa o rarahaneng oa lefa le mokhoa oa taolo oa li-prickles tsa stem mme e re file motheo le lisebelisoa tse ncha tsa ho ithuta baeloji ea rose le ho rafa matšoao a limolek'hule a amanang le litšobotsi tsa bohlokoa.
3. Ho latellana ha Genome ea Synthesized Allopolyploids ho Cucumis e Senola Maikutlo a Genome Evolution ea Allopolyploidization.
Setsi se Kopantsoeng: Univesithi ea Temo ea Nanjing
Journal: Advanced Science
Ntlha ea Tšusumetso: 16.801
Phuputso ena e tlalehile genome ea boleng bo holimo ea allotetraploid ea maiketsetso e fumanoeng ho sebelisoa interspecific hybridization pakeng tsa cucumber (C. sativus, 2n = 14) le mefuta ea eona e hlaha e amanang le eona (C. hystrix, 2n = 24) le katoloso e latelang ea chromosome, e leng eona ea pele. allopolyploid ea maiketsetso e hlophisitsoeng ka botlalo.Kopano ea genome e sebelisitse tatellano ea "PacBio+BioNano+Hi-C+Illumina", e hlahisitse boholo ba genome ea 530.8Mb le contig N50 = 6.5Mb.Ho baloa ho ile ha abeloa li-pseudochromosomes le li-subgenome tse 19.Liphetho li bonts'itse hore ho kopanya, ho fapana le ho pheta-pheta liphatsa tsa lefutso, ho baka boholo ba liphetoho tsa genomic ho bobeli ba nyutlelie le cp genomes.E ile ea fana ka maikutlo a hore heterozygosity e tsitsitseng e fana ka C. × hytivus ka ho eketseha ha khatello ea maikutlo.Liphetho li fana ka leseli le lecha mabapi le phetoho ea limela tsa polyploidy le ho fana ka leano le lebelletsoeng la ho ikatisa bakeng sa lijalo tse tlang.
4.Comparative Genome e Hlahlobisisa Totobatsa Katoloso ea Genome ea Transposon Mediated le Evolutionary Architecture ea 3D Genomic Folding in Cotton
Setsi se Kopantsoeng: Univesithi ea Temo ea Huazhong
Journal: Biology ea Limolek'hule le Evolution
Ntlha ea Tšusumetso: 16.242
Morero ona o sebelisitse Nanopore Sequencing ho kopanya liphatsa tsa lefutso tsa mefuta e meraro ea k'hothone e leng: Gossypium rotundifolium (K2, genome size = 2.44Gb, contigN50 = 5.33Mb), G. arboreum (A2, genome size = 1.62Gb, contig10 = 50), le contigN50. G. raimondii (D5, boholo ba genome = 0.75Gb, contigN50 = 17.04 Gb).Ho feta 99% ea liphatsa tsa lefutso tse tharo li ile tsa kopanngoa ka Hi-C.Liphetho tsa tlhahlobo ea BUSCO ke 92.5%, 93.9% le 95.4% ka ho latellana.Linomoro tsena kaofela li bonts'itse hore liphatsa tsa lefutso tse tharo tsa kopano ke "reference-grade".Liphuputso tsa papiso ea genome li ngotse lintlha tsa ho holisa TE e ikhethileng ea leloko le tlatsetsang phapanong e kholo ea boholo ba genome.Boithuto bona bo fana ka leseli mabapi le karolo ea katoloso ea genome ea transposon-mediated phetohong ea sebopeho sa chromatin se maemong a holimo limeleng.
5. Kopano ea sekala sa chromosome le tlhahlobo ea lijalo tsa biomass Miscanthus lutarioriparius genome
Setsi se Kopantsoeng: Setsi sa CAS sa Bokhabane ho Saense ea Limela tsa Limolek'hule
Journal: Tlhaho ea puisano
Ntlha ea Tšusumetso: 14.912
Morero ona o tlalehile kopano ea chromosome-scale ea Miscanthus lutarioriparius genome ka ho kopanya tatellano ea Oxford Nanopore le theknoloji ea Hi-C.Kopano ea 2.07Gb e akaretsa 96.64% ea genome, e nang le contig N50 ea 1.71 Mb.Hoo e ka bang 94.30% ea tatellano eohle e ile ea kenngoa ho li-pseudochromosomes tse 19.Ka ho bapisa le tatellano ea BAC, tlhahlobo ea LAI, tlhahlobo ea BUSCO, ho kopanya hape le lintlha tsa NGS, ho kopanya hape data ea transcriptome, genome e ile ea hlahlojoa e le ea boleng bo holimo le e tsoelang pele.Tšimoloho ea Allotetraploid ea M. lutarioriparius e tiisitsoe ka ho pheta-pheta satellite ea centromeric.Liphatsa tsa lefutso tsa Tandem duplicate tsa M. lutarioriparius li sebetsa hantle eseng feela mabapi le karabelo ea khatello ea maikutlo, empa biosynthesis ea cell wall.Likopi tsa liphatsa tsa lefutso mohlomong li bapala karolo ho C4 photosynthesis mme li kenya letsoho ho Miscanthus C4 photosynthesis ka mocheso o tlase.Lipatlisiso li fane ka tšupiso ea bohlokoa bakeng sa ho ithuta limela tse sa feleng.
6. Kopano ea boemo ba chromosome Camptotheca acuminata genome e fana ka leseli mabapi le tšimoloho ea tlhaho ea camptothecin biosynthesis.
Setsi se Kopantsoeng: Univesithi ea Sichuan
Journal: Tlhaho ea puisano
Ntlha ea Tšusumetso: 14.912
Morero ona o tlalehile kopano ea boleng bo holimo, ea boemo ba chromosome C. acuminata genome, e nang le boholo ba genome ea 414.95Mb le contingN50 1.47Mb.Re fumane hore C. acuminata e na le boikaketsi bo ikemetseng ba liphatsa tsa lefutso le mefuta e mengata e tsoang ho eona e amana le camptothecin biosynthesis.Phapang e sebetsang ea liphatsa tsa lefutso tsa LAMT le phetoho e ntle ea liphatsa tsa lefutso tse peli tsa SLAS, ka hona, ka bobeli li tlatselitse haholo ho camptothecin biosynthesis ho C. acuminata.Liphello li ile tsa hatisa bohlokoa ba kopano ea boleng bo phahameng ba genome ho khetholla liphetoho tsa liphatsa tsa lefutso mohloling oa phetoho ea metabolite ea bobeli.
7.Allele-defined genome e senola phapang ea biallelic nakong ea ho iphetola ha cassava
Setsi se Kopantsoeng: Akademi ea China ea Lisaense tsa Temo ea Tropical
Journal: Semela sa Limolek'hule
Ntlha ea Tšusumetso: 13.162
Morero ona o bokelletse genome ea litšupiso bakeng sa cassava e nang le contigN50 1.1Mb e sebelisa sethala sa tatellano sa Pacific Biosciences (PacBio).Kamora ho hlahlojoa ke BUSCO, index ea LAI, le 'mapa oa liphatsa tsa lefutso tse phahameng haholo, genome e kopaneng e netefatsoa e le boemo ba tšireletso.Libaka tse sa hlokeng letho li ile tsa fumanoa 'me li-contigs li ile tsa kenngoa ho li-pseudochromosomes tse 18 ho sebelisoa lihokelo tsa Hi-C.Mofuta ona oa litšupiso oa boleng bo holimo le o hlalosoang ke allele bakeng sa cassava o bohlokoa ho tsebahatseng li-bi-allele tse fapaneng ho li-chromosome tse homologous, e leng se lumellang ho lekola phapang le ho bonts'a taolo ea li-bi-allele le matla a tsona a mantlha a ho khanna.E nolofalitse mekhoa e mecha ea ho ikatisa cassava le lijalo tse ling tsa heterozygous haholo.
8. Litlhaloso tsa Genomic mabapi le kholo e potlakileng ea paulownias le ho thehoa ha lefielo la baloi ba Paulownia
Setsi se Kopantsoeng: Univesithi ea Temo ea Henan
Journal: Semela sa Limolek'hule
Ntlha ea Tšusumetso: 13.162
Morero ona o ile oa kopanya genome ea boleng bo holimo ea nyutlelie ea Paulownia fortunei, 511.6 Mb ka boholo, 'me 93.2% ea tatellano e hokahane le li-pseudochromosomes tse 20.Bokhoni bo phahameng ba photosynthetic bo finyelloa ka ho kopanya C3 photosynthesis le crassulacean acid metabolism pathway, e ka 'nang eaba e tlatselitse tloaelong ea ho hōla ka potlako ea lifate tsa paulownia.Sequencing e eketsehileng ea genome ea PaWB phytoplasma, e kopantsoeng le litlhahlobo tsa ts'ebetso, e bontšitse hore phello ea PaWB-SAP54 e sebelisana ka ho toba le Paulownia PfSPLa, e leng eona e bakang ho senyeha ha PfSPLa ka tsela ea ubiquitin-mediated le ho lebisa ho thehoeng ha lefielo la baloi.Lintlha li fane ka lintlha tsa bohlokoa ho baeloji ea paulownias le mokhoa oa ho laola ho thehoa ha PaWB.
Genome ea liphoofolo - Lintlha tse tebileng tsa ho iphetola ha lintho
1.Genome ea Nautilus pompilius e khantša ho iphetola ha mahlo le biomineralization.
Setsi se Kopantsoeng: South China Sea Institute of Oceanology, CAS
Journal: Natural Ecology & Evolution
Lintlha tse amang: 15.462
Morero ona o hlahisitse genome e felletseng bakeng sa Nautilus pompilius.E na le genome e nyane har'a li-cephalopods tse tatellano, e leng 730.58Mb e nang le contigN50 = 1.1Mb.Sephetho sa tlhahlobo ea BUSCO ke 91.31%.Ha e kopantsoe le transcriptome, proteome, gene family and phylogenetic analysis, genome ena e fane ka tšupiso ea motheo mabapi le lintlafatso tsa cephalopod, joalo ka leihlo la pinhole le biomineralization.Patlisiso e bontšitse hore tšenyo e felletseng ea sehlopha sa liphatsa tsa lefutso tsa Hox e kanna ea amana le ho nyamela ha khetla ea Mollusks.Habohlokoa, lintlafatso tse ngata tsa liphatsa tsa lefutso tse kenyelletsang tahlehelo ea liphatsa tsa lefutso, thibelo e ikemetseng le katoloso ea liphatsa tsa lefutso tse ikhethileng le marang-rang a tsona a taolo a ka 'nang a theha phetoho ea leihlo la nautilus pinhole.Nautilus genome e thehile sesebelisoa sa bohlokoa bakeng sa ho aha bocha maemo a ho iphetola ha lintho le boqapi ba genomic bo bopang li-cephalopods tse seng li le teng.
2.Seadragon genome analysis e fana ka leseli mabapi le phenotype ea eona le sebaka sa boikemisetso ba thobalano
Setsi se Kopantsoeng: South China Sea Institute of Oceanology, CAS
Journal: Tsoelo-pele ea Saense
Ntlha ea Tšusumetso: 14.132
Porojeke ena ya diphatsa tsa lefutso tse tona le tse tshehadi tsa seadragon e tlwaelehileng (Phyllopteryx taeniolatus) le mefuta ya yona e amanang haufi-ufi, alligator pipefish (Syngnathoides biaculeatus).Boholo ba genome bakeng sa Phyllopteryx taeniolatus ke ~659 Mb(♂）le ~663 Mb(♀), ka contigN50 ea 10.0Mb le 12.1mb.boholo ba genome bakeng sa Phyllopteryx taeniolatus ke 637 Mb（♂）le ~648 Mb(♀), ka contigN50 ea 18.0Mb le 21.0Mb.Ka tlhahlobo ea phylogenetic, seadragon e tloaelehileng le alligator pipefish ke taxon ea Syngnathinae, 'me e arohane hoo e ka bang 27.3 Mae fetileng.Litlaleho tse ngotsoeng ka mokhoa oa ho iphetola ha lintho, li-appendages tse kang makhasi, li bonts'a hore mefuta e mengata ea liphatsa tsa lefutso e amehang ntlafatsong ea ho qetela e khethiloe hammoho le ntlafatso ea lingoliloeng bakeng sa tokiso ea lisele le mefuta ea ts'ireletso ea 'mele.Ho ile ha hloauoa sebaka se khethollang thobalano e kenyelletsang mofuta oa amhr2y oa banna o arolelanoang ke common seadragon le alligator pipefish.Morero ona o fane ka bopaki ba bohlokoa bakeng sa lithuto tsa ho iphetola ha lintho.
Nako ea poso: Sep-19-2022