BMKGENE e fane ka lits'ebeletso tsa tatellano ea nako e telele ea transcriptome bakeng sa thuto ena : Tatelano e felletseng ea transcriptome ea li-lymphocyte e arabela IFN-γ e senola karabelo ea 'mele ea ho itšireletsa mafung ea Th1 ka flounder (Paralichthys olivaceus), e phatlalalitsoeng ho Fish & shellfish immunology.
Phuputsong ena, tatellano ea nako e telele ea transcriptome e ile ea etsoa ho hlahloba mefuta e fapaneng ea liphatsa tsa lefutso (DEGs) le litsela tsa matšoao ho IFN-γ e tsosolositsoeng ea lymphocyte ea flounder (Paralichthys olivaceus), Th1 le Th2 tsela ea phapang ea lisele e ile ea ntlafatsoa ka mokhoa o tsotehang ho tloha ho DEGs, le liphatsa tsa lefutso tse tseleng ea phapang ea lisele tsa Th1 li ile tsa laoloa le ho netefatsoa.Ka lebaka leo, liphapang tsa liphatsa tsa lefutso tsa lisele tsa Th1 le lisele tsa CD4 + li ile tsa batlisisoa ka mor'a ho tsosoa ha IFN-γ, liphetho li tiisitse hore li-lymphocyte tsa CD4 + T li ile tsa ata haholo ka mor'a ts'usumetso ea IFN-γ, e tsamaeang le liphatsa tsa lefutso tse robeli tsa bohlokoa tsa ho phahama le ho eketseha ha T-bet polelong ea lymphocyte.
Qetellong, liphetho li ile tsa senola ho kenngoa ha IFN-γ ka karabelo ea 'mele ea ho itšireletsa mafung ea mofuta oa Th1, ho fana ka maikutlo a morao-rao ho khethollang CD4 + T lymphocyte ka teleost.
TobetsaMonaho ithuta haholoanyane ka thuto ena.
Nako ea poso: Oct-30-2023