BMKGENE e fane ka lits'ebeletso tsa tatellano ea li-transcriptomics tsa sebaka bakeng sa thuto ena: e ka bang Drosophila homologue ea mammalian adhesion GPCRs, e kenya letsoho liketsong tsa antitumor ho lisele tsa oncogenic tse entsoeng ka lintsintsi, tse phatlalalitsoeng ho PNAS, mthl1.
Thutong ena, lintsintsi tse tona tse kholo li ile tsa entoa ka li-OC, 'me tatellano ea transcriptome ea sebaka ho lintsintsi tse leqhoa e ea etsoa.Ho kenngoa ha li-OC ho lintsintsi tse tona tse kholo ho etsa hore ho be le karabo e matla ho lintsintsi tse amohelang liphatsa tsa lefutso tse kenyelletsang liprotheine tsa 'nete tsa G-coupled, tseo gene ea methusela-like 1 e hlahelletseng.
Ka motsoako oa liphatsa tsa lefutso tsa lefutso la mthl1 (tahlehelo ea ts'ebetso le maikutlo a feteletseng a mthl1), ho ngotsoe hore kannete lefutso lena le na le phello ea antiproliferative.Ho feta moo, bonts'a hore mthl1 e laola polelo ea palo e kholo ea liphatsa tsa lefutso bakeng sa li-chemoreceptors le liphatsa tsa lefutso tse amehang taolong ea nts'etsopele.Hlalosa mekhoa ea ts'ireletso ea lintsintsi khahlanong le lihlahala ka ho ba sieo ha ho itšireletsa mafung.
Tobetsa mona ho ithuta haholoanyane ka boithuto bona
Nako ea poso: Aug-10-2023