BMKGENE e fane ka tšebeletso ea tatellano ea li-transcriptome bakeng sa thuto "Cascade nanoreactor bakeng sa ho ntlafatsa kalafo ea sonodynamic ho mofetše oa colorectal ka synergistic ROS augment le autophagy blockage.", e hatisitsoeng ho Nano Today.
Boithuto bona bo ikemiselitse ho ntlafatsa ts'ebetso ea antitumor ea sonodynamic therapy (SDT) ho mofets'e oa colorectal, ho rala nanoreactor ea cascade ka ho kenyelletsa sonosensitizer Ce6 le autophagy inhibitor chloroquine ka har'a homologous tumor cell membrane-modified hollow polydopamine nanocarrier e kentsoeng pele ka platinozy. (e khethiloe joalo ka CCP@HP@M).
Litlhahlobo tsa RNA-seq li boetse li netefalitse apoptosis le litsela tsa ferroptosis tse amehang kalafong ea CCP@HP@M.Cascade nanoreactor e tla fana ka leano le ts'episang la ho eketsa pheliso ea SDT khahlano le lihlahala ka ho feto-fetoha ha ROS le autophagy.
TobetsaMonaho ithuta haholoanyane ka sengoloa sena.
Nako ea poso: Sep-08-2023