BMKGENE e fane ka litšebeletso tsa tatellano ea Hi-C bakeng sa thuto ena: 3D disorganization le rearrangement ea genome fana ka temohisiso ka pathogenesis ea non-alcoholic mafura a sebete lefu la (NAFLD) ka ho kopantswe Hi-C, Nanopore, le RNA sequencing, e ileng ea hatisoa Acta Pharmaceutica Sinica. B.
Thutong ena, High-throughput chromosome conformation capture (Hi-C), Nanopore sequencing, le litlhahlobo tsa RNA-sequencing (RNA-seq) li ile tsa etsoa sebeteng sa litoeba tse tloaelehileng le tsa NAFLD.
Phapang e bonts'itsoeng libakeng tse likete ho pholletsa le genome mabapi le mokhatlo oa chromatin oa 3D le ho hlophisoa bocha ha genomic, lipakeng tsa litoeba tse tloaelehileng le tsa NAFLD, le ho senoloa ha liphatsa tsa lefutso khafetsa ho tsamaisana le mefuta ena.Liphatsa tsa lefutso tsa mokhethoa li ile tsa khetholloa ho NAFLD, tse anngoeng ke ho hlophisa bocha liphatsa tsa lefutso le ho senyeha ha mokhatlo oa sebaka.
Liphuputso tse ncha li fana ka leseli mabapi le mekhoa e mecha ea NAFLD pathogenesis mme e ka fana ka moralo o mocha oa mohopolo bakeng sa kalafo ea NAFLD.
TobetsaMonaho ithuta haholoanyane ka thuto ena.
Nako ea poso: Oct-30-2023