2021, BMKGENE waxay goob joog u ahayd 31 De novo genome research si guul leh loogu daabacay joornaalada saamaynta sare leh oo leh wadarta guud ee arimaha saamaynta in ka badan 320
Isla ka dib bilowgii sanadka 2022, waxaa horeyba u jiray laba maqaal oo cilmi baaris ah oo lagu daabacay joornaalka "Genetics Dabiiciga ah" iyo "Molecular Plant" siday u kala horreeyaan.Waxay yihiin, "Laba nooc oo kala duwan oo ka soo jeeda genome heterozygous lychee genome ah ayaa soo jeedinaya dhacdooyin madax-bannaan oo loogu talagalay beeralayda hore iyo kuwa dambe" ), iyo "Genome taxanaha shanta nooc ee Sitopsis ee Aegilops iyo asalka sarreenka polyploid B-subgenome" (Shanta noocyada Sitopsis genome, oo ay sameeyeen kooxda cilmi-baarista Professor Bao Liu ee Northeast Normal University.).Waxaan sidoo kale dib u eegi doonaa labadan maqaal oo aan la wadaagi doonaa akhristayaasha.
Haddaba, aan eegno maqaallada cilmi-baarista ee aadka u wanaagsan ee la daabacay 2021 oo ay wada qoreen BMK iyo tas-hiilaadka aan iska kaashanay.
Genome Plant - Horumarrada noocyada badan leh.
1.Gronomy-ga tayada sare leh wuxuu muujiyaa sifooyinka genomic galley iyo hidde-sidaha muhiimka ah ee beeraha
Xarunta la iska kaashaday: Jaamacadda Beeraha ee Henan
Joornaalka: Hiddaha Dabiiciga ah
Saamaynta Saamaynta: 38.31
Mashruucan, genome of Weining rye, oo ah nooc galley ah oo Shiinees ah oo caan ah, ayaa la isku xigsaday.Xirmooyinka la isku keenay (7.74 Gb) waxay ku xisaabtameen 98.47% qiyaasta genome-ga lagu qiyaasay (7.86 Gb), iyadoo 93.67% contigs (7.25 Gb) loo qoondeeyay todoba koromosoom.Curiyayaasha soo noqnoqda waxay ka kooban yihiin 90.31% genome-ga la soo ururiyey.Falanqaynta dheeraadka ah ee golaha Weining waxay iftiimisay iftiin cusub oo ku saabsan hiddo-wadaha hiddo-wadaha-ballaaran iyo saamaynta ay ku leeyihiin hiddo-wadaha biosynthesis istaarijka, abaabulka jireed ee prolamin loci ee kakan, muujinta hidda-wadaha astaamaha asaasiga ah ee ciwaanka hore iyo gobollada koromosoomyada ee laxiriira gudaha gudaha iyo loci ee galley.Tixdan genome-ka ahi waxa ay ballan qaadaysaa in ay dardargeliso cilmi-baadhisyada taranta iyo taranta ee galleyda iyo dalagga dalagga ee la xidhiidha.
2.Rose without prickle: aragtida genomic ee ku xidhan la qabsiga qoyaanka
Xarunta la iska kaashaday: Machadka Kunming ee dhirta, Akadeemiyada Sayniska ee Shiinaha
Joornaalka: Dib u eegista Sayniska Qaranka
Saamaynta Saamaynta: 17.273
Mashruucan, muunadaha 'Basye's Thornless' (BT, beeralayda Rosa wichuraiana), 'Old Blush' (OB, aasaasaha genotype ee qoyska ubaxa), isku-dhafka F1 iyo BCF1 ayaa la ururiyay.Waxaana la sameeyay ururin genome tixraaceed oo tayo sare leh si loo aqoonsado walxaha hidde-sidaha ee la xidhiidha horumarka asliga ah.Cabbirka genome-ku waa qiyaastii 530.6 Mb.Si loo xaqiijiyo tayada genome-ga la soo ururiyey, falanqaynta sida isbarbardhigga khariidadaha hidaha, BUSCO, NGS waxay akhridaa dib-u-ururinta, marka la barbardhigo OB haplotype, xakamaynta heerka qaladka saldhigga ah iyo hubinta qiimaha genome-ballaaran ee LTR Assembly (LAI=20.03) ayaa la sameeyay.Cilmi-baadhistani waxay daaha ka qaadaysaa habka dhaxalka ee kakan iyo habka nidaaminta ee prickles stem waxayna na siisay aasaas iyo ilo cusub oo lagu baranayo bayoolajiga rose iyo calaamadaha miinada ee la xidhiidha sifooyinka muhiimka ah.
3.Taxane-Dhammaan-Genome-ka ee Allopolyploids-ka Isku-dhafka ah ee Cucumis ayaa daaha ka qaadaya aragtiyo ku saabsan Horumarka Genome ee Allopolyploidization
Xarunta la iska kaashaday: Jaamacadda Beeraha ee Nanjing
Joornaalka: Sayniska Sare
Saamaynta Saamaynta: 16.801
Daraasadani waxay soo warisay genome-ga tayada sare leh ee allotetraploid synthetic ee la helay iyadoo la adeegsanayo isku-dhafka is-gaarsiinta ee u dhexeeya qajaarka (C. sativus, 2n = 14) iyo noocyada qaraabada duurjoogta ah (C. hystrix, 2n = 24) iyo nuqulka koromosoomyada xiga, taas oo ah tan ugu horeysa. allopolyploid synthetic oo si buuxda isugu xiga.Isu imaatinka genome-ku wuxuu adeegsaday socodka shaqada ee isku xigxiga "PacBio+BioNano+Hi-C+Illumina", waxay keentay cabbirka genome ee 530.8Mb iyo contig N50 = 6.5Mb.Akhriska waxa loo qoondeeyay 19 pseudochromosomes iyo subgenomes.Natiijooyinku waxay muujiyeen in isku-dhafan, halkii ay ka ahaan lahayd nuqulka genome-ga, ay keento badi isbeddellada genomic ee labadaba nukliyeerka iyo genome cp.Waxay soo jeedisay in heterozygosity go'an ay bixiso C. × hytitus la qabsiga walaaca kordhay.Natiijooyinku waxay bixiyaan fikrado cusub oo ku saabsan kobcinta polyploidy dhirta waxayna bixiyaan istiraatiijiyad taranta mustaqbalka ee dalagga mustaqbalka.
4.Comparative Genome wuxuu falanqeeyaa Iftiinka Transposon Dhexdhexaadin Dhexdhexaadin Balaadhinta hiddo-wadaha iyo Farsamaynta Kobcinta ee 3D Genomic Laabashada ee Cudbiga
Xarunta la iska kaashaday: Jaamacadda Beeraha ee Huazhong
Joornaalka: Biology Molecular iyo Evolution
Saamaynta Saamaynta: 16.242
Mashruucani wuxuu isticmaalay Nanopore Sequencing si uu u ururiyo genome saddex nooc oo cudbi ah oo kala ah: Gossypium rotundifolium (K2, genome size = 2.44Gb, contigN50 = 5.33Mb), G. arboreum (A2, genome size = 1.62Gb, contigN.50) G. raimondii (D5, cabbirka genome = 0.75Gb, contigN50 = 17.04 Gb).In ka badan 99% dhammaan saddexda genome waxaa la isugu keenay Hi-C.Natiijooyinka falanqaynta BUSCO waa 92.5%, 93.9% iyo 95.4% siday u kala horreeyaan.Dhammaan tirooyinkani waxay muujiyeen in saddexda genome-ga kulanka ay yihiin tixraac - daraja.Falanqaynta genome-ka isbarbardhigga ah ayaa diiwaangeliyay faahfaahinta nasabka-gaarka ah ee xoojinta TE ee gacan ka geysta kala duwanaanshaha cabbirka genome-ga weyn.Daraasadani waxay iftiiminaysaa doorka balaadhinta genome-ka dhexdhexaadinta transposon-ka ee horumarka qaab dhismeedka chromatin-ka sare ee dhirta.
5. Isku imaatinka miisaanka koromosoomyada iyo falanqaynta dalagga noole ee Miscanthus lutarioriparius genome
Xarunta la iska kaashaday: Xarunta CAS ee heer sare ee Sayniska Dhirta molecular
Joornaalka: Isgaarsiinta Dabeecadda
Saamaynta Saamaynta: 14.912
Mashruucani waxa uu soo sheegay isu imaatinka miisaanka koromosoomyada ee Miscanthus lutarioriparius genome iyada oo la isku daray taxanaha Oxford Nanopore iyo tignoolajiyada Hi-C.Isku xirka 2.07Gb wuxuu daboolayaa 96.64% genome-ka, oo leh N50 oo ah 1.71 Mb.Qiyaastii 94.30% wadarta taxanaha waxa lagu xidhay 19 pseudochromosomes.Marka la barbardhigo isku xigxiga BAC, qiimaynta LAI, qiimaynta BUSCO, dib-u-ururinta xogta NGS, dib-u-ururinta xogta qoraalka, genome-ka waxaa lagu qiimeeyay mid tayo sare leh iyo sii socosho.Alloteraploid asalka ah ee M. lutarioriparius waa la xaqiijiyay iyadoo la isticmaalayo centromeric dayax gacmeedka.Hidde-sideyaasha tandem ee M. lutarioriparius waa kuwo shaqeynaya oo la hodmay oo keliya maaha marka la eego jawaabta walaaca, laakiin biosynthesis derbiga unugyada.Nuqullada hidda-wadaha waxay u badan tahay inay door ka ciyaaraan sawir-qaadista C4 waxayna gacan ka geystaan sawir-qaadista Miscanthus C4 heerkul hooseeya.Cilmi-baaristu waxay bixisay tixraac muhiim ah oo lagu baranayo dhirta daa'imka ah.
6.Heerka koromosoomyada Camptotheca acuminata genome kulanka wuxuu bixiyaa aragtiyo ku saabsan asalka korriinka ee biosynthesis ee camptothecin
Xarunta la iska kaashaday: Jaamacadda Sichuan
Joornaalka: Isgaarsiinta Dabeecadda
Saamaynta Saamaynta: 14.912
Mashruucani waxa uu soo sheegay heer-koromosoom oo tayo sare leh C. acuminata genome meeting, oo cabirkiisu yahay 414.95Mb iyo ka kooban N50 1.47Mb.Waxaan ogaanay in C. acuminata ay la kulanto isku duubnaan dhan-genome oo madax-bannaan iyo hiddo-sideyaal badan oo ka soo jeeda waxay la xiriiraan biosynthesis kamptothecin.Kala duwanaanshaha shaqeynta ee hiddo-wadaha LAMT iyo kobcinta togan ee laba gen SLAS, sidaas darteed, labaduba waxay si weyn uga qaybqaateen biosynthesis-ka camptothecin ee C. acuminata.Natiijadu waxay xoojisay muhiimada ay leedahay isu imaatinka genome-ga oo tayo sare leh si loo aqoonsado isbeddellada hidde-sidaha ee asalka kobaca ee dheef-shiid kiimikaad sare.
7.Allele-qeexay genome wuxuu daaha ka qaadaa kala duwanaanshaha biillelic inta lagu guda jiro horumarka kasaafada
Xarunta la iska kaashaday: Akademiyada Shiinaha ee Sayniska Beeraha Kulaylaha
Joornaalka: Dhirta molecular
Saamaynta Saamaynta: 13.162
Mashruucani waxa uu soo ururiyey genome tixraaca oo cassava ah oo wata contigN50 1.1Mb iyada oo la adeegsanayo madal isku xigxiga ee Biosciences Pacific (PacBio).Ka dib markii ay qiimeeyeen BUSCO, index LAI, iyo khariidadda hidde-cufnaanta-sare, genome-ga la isku keenay waxaa loo xaqiijiyay heerka tixraac.Gobollada dheeraadka ah ayaa la aqoonsaday waxaana lagu dhejiyay 18 koromosoomyada pseudochromosomes iyadoo la adeegsanayo isku xirka Hi-C.Tixraacan tayada sare leh iyo allele-qeexay genome-ka cassava wuxuu qiimo u leeyahay in la aqoonsado laba-alleles-ka kala duwan ee koromosoomyada isku midka ah, taasoo u oggolaanaysa inay sahamiyaan kala duwanaanshiyaha iyo muujinta awoodda labada-alleles iyo xoogaggooda kobcinta kobcinta.Waxa ay sahashay ikhtiraaca cusub ee taranta cassava iyo dalagyada kale ee aadka u heterozygous.
8. Aragtida genomic ee koritaanka degdega ah ee paulownias iyo samaynta Paulownia xaaqinka saaxiriinta
Xarunta la iska kaashaday: Henan Agricultural university
Joornaalka: Dhirta molecular
Saamaynta Saamaynta: 13.162
Mashruucani waxa uu soo ururiyey genome nukliyeer oo tayo sare leh oo Paulownia fortunei ah, cabbirkiisu dhan yahay 511.6 Mb, iyada oo 93.2% ee taxanayaasha lagu xidhay 20 pseudochromosomes.Waxtarka sare ee sawir-qaadista waxaa lagu gaaraa iyada oo la isku daro C3 photosynthesis iyo dariiqa dheef-shiid kiimikaadka aashitada crassulacean, taas oo laga yaabo inay gacan ka geysato kobaca aadka u degdega ah ee geedaha paulownia.Isku xigxiga genome-ga dheeraadka ah ee PaWB phytoplasma, oo ay weheliso falanqayn hawleed, ayaa muujisay in saamaynta PaWB-SAP54 ay si toos ah ula falgasho Paulownia PfSPLa, taas oo iyaduna keenta hoos u dhaca PfSPLa ee dariiqa dhexdhexaadinta ah ee ubiquitin waxayna u horseedaa samaynta xaaqinka saaxiriinta.Xogtu waxay siisay fikrado muhiim ah oo ku saabsan bayoolajiga paulownias iyo habka sharciyeynta ee samaynta PaWB.
Genom-ga xayawaanka - Aragti qoto dheer oo ku saabsan horumarinta noocyada
1. genome-ka Nautilus pompilius wuxuu iftiimiyaa horumarka indhaha iyo biomineralization
Xarunta la iska kaashaday: South China Institute of Oceanology Sea, CAS
Joornaalka: Ecology Dabiiciga ah & Horumarka
Saamaynta Saamaynta: 15.462
Mashruucani wuxuu soo bandhigay genome dhamaystiran oo loogu talagalay Nautilus pompilius.Waxay leedahay genome-ga ugu yar oo ka mid ah cephalopods taxanaha ah, kaas oo ah 730.58Mb oo leh contigN50 = 1.1Mb.Natiijada qiimaynta BUSCO waa 91.31%.Marka lagu daro transcriptome, proteome, qoyska hiddaha iyo falanqaynta phylogenetic, genome-kani wuxuu bixiyay tixraac aasaasi ah oo ku saabsan hal-abuurka cephalopod, sida isha pinhole iyo biomineralization.Cilmi-baaristu waxay muujisay in dhaawaca ku yimid dhammaystirka kooxda hidda-wadaha Hox ay la xiriirto qolof lumay Mollusks.Muhiimad ahaan, hal-abuuro badan oo genomic ah oo ay ku jiraan luminta hiddo-wadaha, foosha madax-bannaanida iyo ballaarinta qoysaska hidde-sideyaasha gaarka ah iyo shabakadaha sharciyaynta ee la xidhiidha waxay u badan tahay inay qaabeeyaan horumarka isha nautilus pinhole.Genome-ka nautilus wuxuu ka kooban yahay kheyraad qiimo leh oo loogu talagalay dib-u-dhiska xaaladaha kobaca iyo hal-abuurka genomic ee qaabeeya cephalopods-ka jira.
2.Seadragon genome falanqaynta waxay bixisaa aragtiyo ku saabsan phenotype iyo meesha go'aaminta galmada
Xarunta la iska kaashaday: South China Institute of Oceanology Sea, CAS
Joornaalka: Horumarka Sayniska
Saamaynta Saamaynta: 14.132
Mashruucan de novo-Gnomes-ka lab iyo dhedig ee isku xigxiga ee badmareenka caadiga ah (Phyllopteryx taeniolatus) iyo nuucyadiisa dhow, alligator pipefish (Syngnathoides biaculeatus).Cabbirka genome ee Phyllopteryx taeniolatus waa ~ 659 Mb (♂) iyo ~ 663 Mb (♀), oo leh contigN50 ee 10.0Mb iyo 12.1mb.Cabbirka genome ee Phyllopteryx taeniolatus waa 637 Mb (♂) iyo ~ 648 Mb (♀), oo leh contigN50 ee 18.0Mb iyo 21.0Mb.Iyada oo loo marayo falanqaynta phylogenetic, badmareenada caadiga ah iyo pipefish alligator waa walaasha taxo ee Syngnathinae, waxayna kala duwanaayeen qiyaastii 27.3 Ma ka hor.Qoraallada qoraallada laga soo qaatay horumar cusub, lifaaqyada caleen u eg, ayaa muujinaya in hiddo-wadayaal sida caadiga ah ku lug leh horumarinta finka la isku daray iyo sidoo kale kobcinta qoraallada qoraalka ah ee dayactirka unugyada suurtagalka ah iyo hiddo-wadaha difaaca difaaca.Galmo fiiqan-go'aaminaya meesha codeeya hidde-sidaha amhr2y ee lab-gaar ah ee ay wadaagaan badeedka caadiga ah iyo pipefish aligator ayaa la aqoonsaday.Mashruucani wuxuu bixiyay caddayn muhiim ah oo loogu talagalay daraasadaha horumarinta la qabsiga.
Waqtiga boostada: Seb-19-2022