BMKGENE waxay bixisay adeegyo taxane RNA ah oo dheer oo aan codeeyn maqaalka "Nanoformula of zoledronic acid iyo calcium carbonate bartilmaameedyada osteoclasts oo beddelaa osteoporosis", kaas oo lagu daabacay Biomaterials, halkan, OCs' nanoplatform-HMCZP ka jawaabaan microenvironment-nanoplatform ayaa la sameeyay.
Daraasadu waxay muujinaysaa in HMCZP ay waxtar badan u leedahay joojinta dhaqdhaqaaqa OCs ee qaan-gaarka ah iyo dib u celinta lafaha nidaamka ee jiirarka ugxan-sidaha marka la barbar dhigo daaweynta safka hore.Isku-xigta sare ee RNA (RNA-seq) ayaa shaaca ka qaaday in HMCZP ay hoos u dhigi karto bartilmaameedka muhiimka ah ee lafaha, fosfatase acid tartrate u adkaysta (TRAP), iyo bartilmaameedyada kale ee daaweynta ee suurtagalka ah.Natiijooyinkani waxay soo jeedinayaan in isticmaalka nanoplatform caqli-gal ah oo bartilmaameedsada OC-yada ay tahay istaraatijiyad rajo leh oo ku saabsan daaweynta lafo-jileecu.
Gujihalkansi aad wax badan uga barato daraasaddan.
Waqtiga boostada: Dec-20-2023