BMKGENE waxay bixisay adeegyada isku xigxiga Hi-C ee daraasaddan: Habaynta 3D iyo dib-u-habaynta genome waxay bixisaa aragtiyo ku saabsan cudurka beerka dufanka leh ee aan khamriga ahayn (NAFLD) ee isku-dhafka Hi-C, Nanopore, iyo RNA, kaas oo lagu daabacay Acta Pharmaceutica Sinica B.
Daraasaddan, qabsashada koromosoomyada sare ee koromosoomyada (Hi-C), taxanaha Nanopore, iyo RNA-sequencing (RNA-seq) ayaa lagu sameeyay beerka caadiga ah iyo jiirarka NAFLD.
Kala duwanaanshiyaha la aqoonsaday ee kumanaanka gobol ee genome-ga marka loo eego ururka 3D chromatin iyo dib u habeynta genomic, inta u dhaxaysa jiirarka caadiga ah iyo NAFLD, oo shaaca ka qaaday habacsanaanta hidda-wadaha oo ay la socdaan kala duwanaanshiyahan.Hidde-sideyaasha bartilmaameedka ah ee musharraxiinta ayaa lagu aqoonsaday NAFLD, oo ay saamaysay dib-u-habaynta hidde-socodyada iyo carqaladaynta ururrada goobta.
Natiijooyinka cusubi waxay bixiyaan fikrado ku saabsan hababka cusub ee NAFLD pathogenesis waxayna bixin karaan qaab-dhismeedka cusub ee daaweynta NAFLD.
Gujihalkansi aad wax badan uga barato daraasaddan.
Waqtiga boostada: Oct-30-2023