BMKGENE yakapa marefu asingaverengeki eRNA sequencing masevhisi echinyorwa "Iyo nanoformula yezoledronic acid uye calcium carbonate inotarisa osteoclasts uye inodzosera osteoporosis", iyo yakabudiswa muBiomaterials, pano, an OCs 'microenvironment-responsive nanoplatform-HMCZP inogadzirwa.
Chidzidzo chacho chinoratidza kuti HMCZP inonyanya kushanda mukudzivisa maOCs akura basa uye kudzorera systemic kurasikirwa kwemafupa mumakonzo e ovariectomized kana ichienzaniswa nerapi yekutanga.High-throughput RNA sequencing (RNA-seq) yakaratidza kuti HMCZP inogona kudzika-kugadzirisa chinangwa chakakosha che osteoporosis, tartrate-resistant acid phosphatase (TRAP), uye zvimwe zvingangoitika zvekurapa.Izvi zvakawanikwa zvinoratidza kuti kushandisa yakangwara nanoplatform inonangana neOCs izano rinovimbisa reosteoporosis therapy.
Dzvanyaherekuti mudzidze zvakawanda nezvechidzidzo ichi.
Nguva yekutumira: Zvita-20-2023