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BMKGENE yakapa yakazara-yakareba transcriptome sequencing masevhisi echidzidzo ichi : Yakazara-yakareba transcriptome sequencing ye lymphocytes inopindura IFN-γ inoburitsa Th1-skewed immune immune reaction in flounder (Paralichthys olivaceus), iyo yakabudiswa muFish & shellfish immunology.

Muchidzidzo ichi, yakazara-yakareba transcriptome sequencing yakaitwa kuti iongorore maitiro akasiyana-siyana (DEGs) uye nzira dzechiratidzo muIFN-γ yakakurudzira lymphocytes ye flounder (Paralichthys olivaceus), Th1 uye Th2 nzira yekusiyanisa masero yakasimbiswa zvinoshamisa kubva kuDEGs, uye majini ari muTh1 cell differentiation nzira yakagadziriswa uye yakasimbiswa.Saizvozvowo, kusiyana kweTh1 cell differentiation marker genes uye CD4 + masero akaongororwa mushure mekusimudzira IFN-γ, zvigumisiro zvakasimbisa kuti CD4 + T lymphocytes yakawedzera zvakanyanya mushure mekusimudzira IFN-γ, ichiperekedzwa nemajini masere akakosha kukwira uye kuwedzera T-bheti kutaura mu lymphocytes.

Mukupedzisa, zvigumisiro zvakaratidza kuiswa kweIFN-γ pane Th1-mhando yekudzivirira zvirwere, ichipa maonero matsva mukusiyanisa CD4 + T lymphocytes mu teleost.

Dzvanyaherekuti mudzidze zvakawanda nezvechidzidzo ichi.


Nguva yekutumira: Oct-30-2023

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