BMKGENE yakapa spatial transcriptomics sequencing masevhisi echidzidzo ichi: inogona Drosophila homologue ye mammalian adhesion GPCRs, inobatanidzwa mukuita antitumor kumajekiseni oncogenic maseru munhunzi, iyo yakaburitswa muPNAS, mthl1.
Muchidzidzo ichi, nhunzi dzechirume dzakabaiwa maOC, uye kutevedzana kwenzvimbo panhunzi dzakaoma nechando kunoitwa.Jekiseni reOCs munhunzi dzechirume huru rinoita kuti nhunzi dzive nemhinduro dzakasimba dzinosanganisira magene encoding Bonafide G-coupled proteins, pakati peiyo geni remethuselah-like 1 rine mukurumbira.
Kuburikidza nekubatanidzwa kwemajini manipulations e mthl1 gene (kurasikirwa kwekushanda uye kuwedzeredza kwemthl1), yakanyorwa kuti zvirokwazvo iyi gene ine antiproliferative effect.Kupfuurirazve, ratidza kuti mthl1 inodzora kutaura kwenhamba huru yemajini coding ye chemoreceptors uye majini anosanganisirwa mukugadzirisa kwekusimudzira.Deciphered nzira dzekudzivirira dzenhunzi kurwisa mamota mukushaikwa kweiyo adaptive immunity.
Dzvanya pano kuti udzidze zvakawanda nezvechidzidzo ichi
Nguva yekutumira: Aug-10-2023