DNA methylation ndeimwe yeakanyanya kudzidzwa epigenetic shanduko.Inobata basa rakakosha mukugadzikana kwegenome, gene transcription regulation, uye hunhu hwekuvandudza.Kunyorwa kwemajini kunotemerwa nechimiro chavo chemethylation, ine yakaderera methylation mazinga anoenderana nejini kutaura uye yakakwirira methylation mazinga ane chekuita nekunyarara kwemajini.
Kubatanidza whole-genome bisulfite sequencing (WGBS) uye RNA-seq data inobvumira kuongororwa kwakadzama kweiyo genome uye transcriptome, kuburitsa maitiro ekudzora magene, uye kuona nzira dzinoverengeka dzebiology uye biomarkers.Iko kushamwaridzana pakati pezvinyorwa uye methylation sequencing data inogona kugadzwa zvichienderana nemajini, kubatanidza ese ari maviri dataset uchishandisa majini sebhiriji.
Ongororo iyi inobatsira kunzwisisa kuwirirana pakati peDNA methylation uye gene expression, kuona majini anopesvedzerwa nemethylation, uye kuongorora yakadzika mashandiro anoita.
Inzwa wakasununguka kubata BMKGENE kuti uwane ruzivo rusingaenzaniswi mune epigenetic research.
Nguva yekutumira: Zvita-05-2023