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Ibimera / Inyamaswa De novo Urukurikirane rwa Genome
De novoGukurikirana bivuga kubaka ubwoko bwubwoko bwose ukoresheje tekinoroji ikurikirana, urugero nka PacBio, Nanopore, NGS, nibindi, iyo hatabayeho genome.Iterambere ritangaje mubisomwa byuburebure bwikurikiranya rya gatatu byazanye amahirwe mashya yo guteranya genome zigoye, nkizifite ubutumburuke bukabije, igipimo kinini cy’uturere dusubiramo, polyploide, nibindi hamwe nuburebure bwasomwe kurwego rwa kilobase icumi, ibi bisomwa bikurikirana birashoboka gukemura ibintu bisubiramo, uturere dufite ibintu bidasanzwe bya GC nibindi bice bigoye cyane.
Ihuriro ： PacBio Urukurikirane rwa II / Nanopore PromethION P48 / Illumina NovaSeq6000
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Muraho-C ishingiye ku Nteko rusange
Hi-C nuburyo bwateguwe bwo gufata chromosome iboneza muguhuza probe hafi yimikoranire ishingiye kumurongo hamwe no kwinjiza byinshi.Imbaraga ziyi mikoranire zizera ko zifitanye isano mbi nintera yumubiri kuri chromosomes.Kubwibyo, Hi-C amakuru ashobora kuyobora ihuriro, gutondekanya no kwerekana icyerekezo gikusanyirijwe mumushinga wa genome no guhuza ibyo kuri numero runaka ya chromosomes.Iri koranabuhanga riha imbaraga chromosome yo murwego rwa genome mugihe hatabayeho ikarita ishingiye kubaturage.Buri genome imwe ikenera Hi-C.
Ihuriro ： Illumina NovaSeq6000 / DNBSEQ
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Ubwihindurize
Imiterere y'ubwihindurize ni serivisi ikurikiranye igamije gutanga ibisobanuro birambuye ku makuru y'ubwihindurize y'ibikoresho byatanzwe bishingiye ku guhindagurika kw'ibinyabuzima, harimo SNPs, InDels, SVs na CNVs.Itanga isesengura ryibanze risabwa mugusobanura impinduka zubwihindurize nibiranga ubwoko bwabaturage, nkimiterere yabaturage, ubwoko butandukanye, imibanire ya phylogene, nibindi.
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Kugereranya Genomika
Kugereranya genomics mubyukuri bisobanura kugereranya genome yuzuye hamwe nuburyo bwubwoko butandukanye.Iyi disipuline igamije kwerekana ubwihindurize bwibinyabuzima, imikorere ya gene, uburyo bwo kugenzura imiterere ya gen mu rwego rwo kumenya imiterere n'ibintu byakurikiranye cyangwa bitandukanya amoko atandukanye.Ubushakashatsi bugereranya genomics burimo gusesengura mumuryango wa gene, iterambere ryubwihindurize, kwigana genome yose, igitutu cyo guhitamo, nibindi.
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Isesengura ryinshi rya Segregant
Isesengura ryinshi (BSA) nubuhanga bukoreshwa mukumenya byihuse ibimenyetso bya genotype.Ibikorwa nyamukuru bya BSA bikubiyemo gutoranya amatsinda abiri yabantu bafite fenotipike irwanya cyane, guhuza ADN yabantu bose kugirango babeho ibice bibiri bya ADN, bikerekana itandukaniro riri hagati yibidendezi bibiri.Ubu buhanga bwakoreshejwe cyane mukumenya ibimenyetso bya genetike bifitanye isano na gen zigenewe ibimera / inyamaswa.
