SLAF-seq, a high-effective and accurate way to detect variants and develop biomarkers.
A quick overview of SLAF from principle to material selection.
SLAF-seq is a simplified genome sequencing technology independently developed by Biomarker, which can significantly reduce the experimental cost by sequencing part of the genome sequence of species. According to the characteristics of the genome of, SLAF-seq can flexibly select restrictive endonuclease combinations for enzymatic digestion of the DNA, and then select the specific length of the enzymatic fragments for sequencing, so as to ensure a high number of developed markers and realize uniform distribution of markers in the genome at the same time. Based on the variant info we obtained from SLAF, we can further conduct genetic research like GWAS and Evolutionary Genetics to locate the trait-associated gene or explore the evolutionary history among samples. We are willing to share our experience in SLAF sequencing to help with a quick overview of SLAF sequencing on material selection, experiment, downstream genetic analysis, and help researchers to tell a good genetic story of their materials.
In this seminar, you will be learning about
1. Basics and principles of SLAF
2. Advantages of SLAF
3. Service workflow of SLAF
4. Materials selection for SLAF and corresponding genetic analysis
5. Reference cases