BMKGENE inapereka ntchito zazitali zosalemba za RNA zotsatizana ndi nkhani yakuti "Nanoformula ya zoledronic acid ndi calcium carbonate imayang'ana osteoclasts ndi reverses osteoporosis", yomwe inasindikizidwa mu Biomaterials, apa, nanoplatform-HMCZP ya OCs 'microenvironment-responsive-HMCZP yapangidwa.
Kafukufukuyu akuwonetsa kuti HMCZP imakhala yothandiza kwambiri poletsa ntchito za OCs okhwima komanso kubwezeretsa kuwonongeka kwa mafupa mu mbewa za ovariectomized poyerekeza ndi mankhwala oyamba.Kutsata kwapamwamba kwa RNA (RNA-seq) kunawulula kuti HMCZP ikhoza kuchepetsa-kuwongolera chandamale chovuta kwambiri cha osteoporosis, tartrate-resistant acid phosphatase (TRAP), ndi zolinga zina zochizira.Zotsatirazi zikusonyeza kuti kugwiritsa ntchito nanoplatform yanzeru yomwe imayang'ana ma OCs ndi njira yodalirika yochizira matenda a osteoporosis.
DinaniPanokuti mudziwe zambiri za phunziroli.
Nthawi yotumiza: Dec-20-2023