BMKGENE inapereka utali wonse wa transcriptome sequencing ntchito za phunziroli : Full-atali transcriptome sequencing of lymphocytes respond to IFN-γ imasonyeza Th1-skewed immune reaction in flounder (Paralichthys olivaceus), yomwe inasindikizidwa mu Fish & shellfish immunology.
Mu phunziro ili, kutsatizana kwautali wamtundu wa transcriptome kunachitika kuti kusanthula jini (DEGs) ndi njira zowonetsera mu IFN-γ zolimbikitsa ma lymphocytes a flounder (Paralichthys olivaceus), Th1 ndi Th2 cell differentiation njira inalemeretsedwa modabwitsa kuchokera ku DEGs, ndi jini mu njira yosiyanitsa ma cell a Th1 adasinthidwa ndikutsimikiziridwa.Momwemo, kusiyana kwa majeremusi osiyanitsa ma cell a Th1 ndi maselo a CD4 + adafufuzidwa pambuyo pa kukondoweza kwa IFN-γ, zotsatira zake zinatsimikizira kuti CD4 + T lymphocytes inakula kwambiri pambuyo pa IFN-γ kukondoweza, limodzi ndi ma jini asanu ndi atatu akuwongolera kwambiri komanso kuwonjezeka kwa T-bet kufotokozera mu lymphocytes.
Pomaliza, zotsatira zake zidawulula kulowetsedwa kwa IFN-γ pamtundu wa chitetezo chamthupi cha Th1, kupereka malingaliro atsopano pakusiyanitsa ma CD4 + T lymphocytes mu teleost.
DinaniPanokuti mudziwe zambiri za phunziroli.
Nthawi yotumiza: Oct-30-2023