BMKGENE inapereka ntchito yotsatizana ya transcriptome pa phunziroli "Cascade nanoreactor yopititsa patsogolo chithandizo cha sonodynamic pa khansa ya colorectal kudzera mu synergistic ROS augment ndi autophagy blockage.", yomwe idasindikizidwa mu Nano Today.
Kafukufukuyu akufuna kupititsa patsogolo mphamvu ya antitumor ya sonodynamic therapy (SDT) pa khansa yapakhungu, kupanga mwanzeru nanoreactor ya cascade mwa kuphatikiza sonosensitizer Ce6 ndi autophagy inhibitor chloroquine mu homologous chotupa cell membrane-modified hollow polydopamine nanocarrier yomwe imayikidwa kale ndi platinozy plati. (yotchedwa CCP@HP@M).
Kusanthula kwa RNA-seq kunatsimikiziranso njira za apoptosis ndi ferroptosis zomwe zimakhudzidwa ndi chithandizo cha CCP@HP@M.Cascade nanoreactor iyi ipereka njira yodalirika yowonjezerera kuthetseratu kwa SDT motsutsana ndi zotupa posintha ROS ndi autophagy.
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Nthawi yotumiza: Sep-08-2023