BMKGENE inapereka ntchito zotsatizana za Hi-C pa phunziroli: Kusokonezeka kwa 3D ndi kukonzanso ma genome kumapereka chidziwitso cha matenda a chiwindi chamafuta osaledzeretsa (NAFLD) mwa kuphatikizika kwa Hi-C, Nanopore, ndi RNA, komwe kudasindikizidwa mu Acta Pharmaceutica Sinica. B.
Mu phunziro ili, High-throughput chromosome conformation capture (Hi-C), Nanopore sequencing, ndi RNA-sequencing (RNA-seq) anachitidwa pa chiwindi cha mbewa zachibadwa ndi NAFLD.
Kuzindikirika kosiyanasiyana m'magawo masauzande ambiri kudera lonse la ma genome molingana ndi bungwe la 3D chromatin ndikusinthanso ma genomic, pakati pa mbewa zabwinobwino ndi NAFLD, ndikuwulula kusokonekera kwa majini komwe kumatsagana ndi izi.Ma jini omwe amafunsidwa adadziwika mu NAFLD, okhudzidwa ndi kukonzanso ma genetic komanso kusokonezeka kwa malo.
Zomwe zapezazi zimapereka chidziwitso mu njira zatsopano za NAFLD pathogenesis ndipo zimatha kupereka lingaliro latsopano la mankhwala a NAFLD.
DinaniPanokuti mudziwe zambiri za phunziroli.
Nthawi yotumiza: Oct-30-2023