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Application of Nanopore long-read resequencing in the fight against disease
HUMAN GENOMICS nature genetics Long-read sequencing identifies GGC repeat expansions in NOTCH2NLC associated with neuronal intranuclear inclusion disease ONT resequencing | Illumina | Whole exome sequencing | CRISPR-Cas9 ONT targeted sequ...Read more -
Application of Nanopore-based re-sequencing in COVID19 genetic variants identification
WHOLE GENOME RESEQUENING Genomics monitoring of SARS-CoV-2 uncovers an Nsp1 deletion variant that modulates type I interferon response Nanopore | Illumina | Whole genome resequencing | metagenomics | RNA-Seq | Sanger Bioma...Read more -
Structure variants in Chinese population and their impact on phenotypes, diseases and population adaptation
WHOLE GENOME RESEQUENCING Structure variants in Chinese population and their impact on phenotypes, diseases and population adaptation Nanopore | PacBio | Whole genome re-sequencing | Structural variation callling In this s...Read more -
Four telomere-to-telomere assembled animal and plant genomes
T2T GENOME ASSEMBLY, GAP FREE GENOME 1st Two Rice Genomes1 Title: Assembly and Validation of Two Gap-free Reference Genomes for Xian/indica Rice Reveals Insights into Plant Centromere Architecture Doi: https://doi.org/10.1101/2020.12.24.424073 Post...Read more -
Genome sequences reveal global dispersal routes and suggest convergent genetic adaptations in seahorse evolution
GENOME EVOLUTION nature COMMUNICATIONS Genome sequences reveal global dispersal routes and suggest convergent genetic adaptations in seahorse evolution PacBio | Illumina | Hi-C | WGS | Genetic Diversity | Demographic History | Gene Flow Th...Read more -
A high-quality genome assembly highlights rye genomic characteristics and agronomically important genes
GENOME EVOLUTION nature genetics A high-quality genome assembly highlights rye genomic characteristics and agronomically important genes PacBio | Illumina | Bionano Optical Map | Hi-C Genome Assembly | Genetic Map | Selective Sweeps | RNA...Read more -
Chromosome-scale assembly and analysis of biomass crop Miscanthus lutarioriparius genome
GENOME Chromosome-scale assembly and analysis of biomass crop Miscanthus lutarioriparius genome Nanopore sequencing | Illumina | Hi-C | RNA-sequencing | Phylogeny In this study, Biomarker Techno...Read more -
The genome of Nautilus pompilius illuminates eye evolution and biomineralization
GENOME EVOLUTION The genome of Nautilus pompilius illuminates eye evolution and biomineralization PacBio sequencing | Illumina | Phylogenetic analysis | RNA sequencing | SEM | Proteomics ...Read more -
Comparative genome analyses highlight transposon-mediated genome expansion and the evolutionary architecture of 3D genomic folding in cotton
GENOME EVOLUTION Comparative genome analyses highlight transposon-mediated genome expansion and the evolutionary architecture of 3D genomic folding in cotton Nanopore sequencing | Hi-C | PacBio ...Read more -
Genes associated with stress tolerance, oil content, seed quality and ecotype improvement were identified by GWAS in rapeseed
GWAS Title: Whole-genome resequencing reveals Brassica napus origin and genetic loci involved in its improvement Journal: Nature Communications NGS | WGS | Resequencing | GWAS | Transcriptome | RNAseq | Brassica napus | Evolution | Domestic...Read more -
Pan-genome studies provide deep and full genetic views of a species
GENOME EVOLUTION, PANGENOME What is Pan-genome? Accumulated evidences show that variance between different strains of a species can be huge. One single genome is far from enough to gain the whole picture of genetic information of a single species. T...Read more -
Application of Specific-locus amplified fragment sequencing(SLAF-Seq) in genetic marker discovery
High-throughput genotyping, especially on large-scale population, is a fundamental step in genetic association studies, which provides genetic basis for functional gene discovery, evolutionary analysis, etc. Instead of deep whole genome re-sequencing, reduced representat...Read more -
The evolutionary origin and domestication history of goldfish (Carassius auratus)
GENOME EVOLUTION PNAS The evolutionary origin and domestication history of goldfish (Carassius auratus) PacBio | Illumina | Bionano Genome Map | Hi-C Genome Assembly | Genetic Map | GWAS | RNA-Seq Hig...Read more
