I whakaratohia e BMKGENE he ratonga raupapa tuhinga mo te ako "He nanoreactor cascade mo te whakarei ake i te rongoa sonodynamic i runga i te mate pukupuku colorectal ma te synergistic ROS augment me te aukati autophagy", i whakaputaina i roto i te Nano Today.
Ko tenei rangahau e whai ana ki te whakapai ake i te kaha antitumor o te rongoa sonodynamic (SDT) i runga i te mate pukupuku colorectal, te hoahoa tika i te nanoreactor cascade ma te whakauru i te sonosensitizer Ce6 me te chloroquine aukati autophagy ki roto i te homologous tumo cell membrane-whakarerekehia hollow polydopamine nanocarrier i mua-doped ki te nanozymes platinum. (kua tohua hei CCP@HP@M).
Ko nga tātaritanga RNA-seq i whakapumautia ano te apoptosis me nga huarahi ferroptosis e uru ana ki te maimoatanga CCP@HP@M.Ka whakaratohia e tenei nanoreactor cascade he rautaki whakatairanga mo te whakanui i te whakakorenga SDT ki nga pukupuku ma te whakarereketanga o te ROS me te autophagy.
Pāwhirikoneiki te ako atu mo tenei tuhinga.
Te wa tuku: Sep-08-2023