BMKGENE nyere ọrụ nhazi transcriptome zuru oke maka ọmụmụ ihe a: usoro transcriptome zuru oke nke lymphocytes na-azaghachi na IFN-γ na-ekpughe nzaghachi mgbochi Th1-skewed na flounder (Paralichthys olivaceus), nke e bipụtara na Fish & shellfish immunology.
N'ime ọmụmụ ihe a, a na-eme usoro transcriptome zuru oke iji nyochaa mkpụrụ ndụ ihe nketa dị iche iche (DEGs) na ụzọ mgbaàmà na IFN-γ na-akpali lymphocytes nke flounder (Paralichthys olivaceus), Th1 na Th2 cell ụzọ ọdịiche dị ịrịba ama site na DEGs, na mkpụrụ ndụ ihe nketa dị n'okporo ụzọ dị iche iche cell Th1 ka edoziri ma kwenye.N'ihi ya, a na-enyocha ọdịiche dị na mkpụrụ ndụ ihe dị iche iche nke mkpụrụ ndụ Th1 cell na sel CD4 + mgbe mkpali IFN-γ gasịrị, nsonaazụ ahụ gosipụtara na CD4 + T lymphocytes mụbara nke ọma mgbe mkpali IFN-γ gasịrị, tinyere mkpụrụ ndụ asatọ dị ịrịba ama na mmụba T-bet na lymphocytes.
Na mmechi, nsonaazụ ya kpughere ntinye nke IFN-γ na nzaghachi mgbochi Th1, na-enye echiche ọhụụ n'ịwapụta CD4+ T lymphocytes na teleost.
PịaEbe aka ịmatakwu gbasara ọmụmụ ihe a.
Oge nzipu: Ọktoba 30-2023