BMKGENE nyere ọrụ usoro transcriptomics spatial transcriptomics maka ọmụmụ ihe a: enwere ike Drosophila homologue nke mammalian adhesion GPCRs, na-etinye aka na mmeghachi omume antitumor na mkpụrụ ndụ oncogenic agbanyere na ijiji, nke e bipụtara na PNAS, mthl1.
N'ime ọmụmụ ihe a, a gbanyere ijiji nwoke toro eto na OC, a na-eme usoro transcriptome spatial transcriptome na ijiji oyi kpọnwụrụ akpọnwụ.Ngwunye nke OC n'ime ijiji nwoke toro eto na-ebute nzaghachi transcriptomic siri ike na ijiji ndị ọbịa na-egosipụta akpan akpan mkpụrụ ndụ ihe nketa na-edobe protein ndị nwere njikọ G-coupled, n'ime nke mkpụrụ ndụ ihe nketa maka methuselah-dị ka 1 pụtara.
Site na nchikota nke mkpụrụ ndụ ihe nketa mkpụrụ ndụ ihe nketa nke mthl1 gene (efunahụ ọrụ na oke okwu nke mthl1), depụtara na n'ezie mkpụrụ ndụ ihe nketa a nwere mmetụta mgbochi.Ọzọkwa, gosi na mthl1 na-achịkwa okwu nke ọnụ ọgụgụ buru ibu nke mkpụrụ ndụ ihe nketa nzuzo maka chemoreceptors na mkpụrụ ndụ ihe nketa metụtara na nhazi nke mmepe.Deciphered agbachitere usoro ijiji megide etuto ahụ na-anọghị nke ime mgbanwe mgbochi.
Pịa ebe a ka ịmatakwu gbasara ọmụmụ ihe a
Oge nzipu: Ọgọst-10-2023