BMKGENE nyere ọrụ nhazi transcriptome maka ọmụmụ ihe ahụ "A cascade nanoreactor maka ịkwalite ọgwụgwọ sonodynamic na ọrịa cancer colorectal site na mgbakwunye ROS synergistic na mgbochi autophagy.", nke e bipụtara na Nano Today.
Ọmụmụ ihe a na-achọ imeziwanye arụmọrụ antitumor nke sonodynamic therapy (SDT) na ọrịa cancer colorectal, na-eji ezi uche na-emepụta cascade nanoreactor site na itinye sonosensitizer Ce6 na autophagy inhibitor chloroquine n'ime homologous tumor cell membrane-modified hollow polydopamine nanocarrier nke bụ pre-dobere na platinnoped. (akpọrọ aha CCP@HP@M).
Nyocha RNA-seq gosikwara apoptosis na ụzọ feroptosis metụtara ọgwụgwọ CCP@HP@M.Nanoreactor cascade a ga-enye atụmatụ dị mma maka ịkwalite mkpochapụ SDT megide etuto ahụ site na mgbanwe nke ROS na autophagy.
PịaEbe aka ịmatakwu gbasara akụkọ a.
Oge nzipu: Sep-08-2023