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ọkọlọtọ-03

Ngwaahịa

circ-RNA

Circular RNA (circRNA) bụ ụdị RNA na-abụghị koodu, bụ nke achọpụtara n'oge na-adịbeghị anya na-arụ ọrụ dị mkpa na netwọk nchịkwa na-etinye aka na mmepe, nguzogide gburugburu ebe obibi, wdg. Dị iche na mkpụrụ ndụ RNA linear, dịka mRNA, lncRNA, 3' na 5′ A na-ejikọta nsọtụ circRNA ọnụ iji mepụta okirikiri okirikiri, nke na-azọpụta ha na mgbari nke exonuclease ma kwụsie ike karịa ọtụtụ RNA linear.Achọpụtala CircRNA nwere ọrụ dị iche iche n'ịhazi okwu mkpụrụ ndụ ihe nketa.CircRNA nwere ike ịrụ dị ka ceRNA, nke na-ejikọta miRNA na asọmpi, nke a maara dị ka sponge miRNA.Usoro nyocha usoro nke CircRNA na-enye ikike nhazi circRNA na nyocha okwu, amụma ebumnuche na nyocha njikọta na ụdị ụmụ irighiri RNA ndị ọzọ.


Nkọwa ọrụ

Usoro ọrụ bioinformatics


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  • Bioinformatics

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