BMKGENE tau muab cov kev pabcuam ua tiav tag nrho rau qhov kev tshawb fawb no: Cov ntaub ntawv teev sijhawm ntev ntawm cov lymphocytes teb rau IFN-γ qhia txog Th1-skewed tiv thaiv kab mob hauv flounder (Paralichthys olivaceus), uas tau luam tawm hauv Ntses & shellfish immunology.
Nyob rau hauv txoj kev tshawb no, tag nrho-length transcriptome sequencing tau ua los soj ntsuam qhov sib txawv ntawm cov noob caj noob ces (DEGs) thiab qhia txoj hauv kev hauv IFN-γ txhawb nqa lymphocytes ntawm flounder (Paralichthys olivaceus), Th1 thiab Th2 cell sib txawv txoj hauv kev tau zoo kawg li txhawb nqa los ntawm DEGs, thiab Cov noob nyob rau hauv txoj kev sib txawv ntawm Th1 cell tau raug kho thiab txheeb xyuas.Raws li, kev hloov pauv ntawm Th1 cell sib txawv cim cim cov noob thiab CD4 + hlwb tau tshawb xyuas tom qab IFN-γ stimulation, cov txiaj ntsig tau lees paub tias CD4 + T lymphocytes proliferated loj tom qab IFN-γ stimulation, nrog rau yim noob caj noob ces tseem ceeb upregulation thiab nce T-bet qhia nyob rau hauv lymphocytes.
Hauv kev xaus, cov txiaj ntsig tau nthuav tawm qhov kev cuam tshuam ntawm IFN-γ ntawm Th1-hom kev tiv thaiv kab mob, muab cov kev xav tshiab rau hauv kev sib txawv ntawm CD4 + T lymphocytes hauv teleost.
Nyemntawm nokom paub ntau ntxiv txog qhov kev kawm no.
Post lub sij hawm: Oct-30-2023