BMKGENE muab cov kev pabcuam sau tseg rau kev kawm "Lub cascade nanoreactor rau kev txhim kho kev kho sonodynamic ntawm mob qog nqaij hlav hauv plab los ntawm kev sib koom ua ke ROS augment thiab autophagy blockage", uas tau luam tawm hauv Nano Hnub No.
Txoj kev tshawb no aims los txhim kho lub antitumor efficiency ntawm sonodynamic therapy (SDT) ntawm mob qog noj ntshav, rationally tsim ib tug cascade nanoreactor los ntawm incorporating sonosensitizer Ce6 thiab autophagy inhibitor chloroquine rau hauv homologous qog cell membrane-hloov hollow polydopamine nanocarrier uas yog pre-dozynomes nrog platinum. (tsim yog CCP@HP@M).
RNA-seq soj ntsuam kuj tau lees paub tias apoptosis thiab ferroptosis txoj hauv kev koom nrog hauv CCP@HP@M kho.Qhov no cascade nanoreactor yuav muab lub tswv yim zoo rau augmenting SDT tshem tawm cov qog los ntawm kev hloov kho ntawm ROS thiab autophagy.
Nyemntawm nokom paub ntau ntxiv txog kab lus no.
Post lub sij hawm: Sep-08-2023