BMKGENE muab cov kev pabcuam Hi-C sequencing rau txoj kev tshawb no: 3D disorganization thiab rearrangement ntawm genome muab kev nkag siab rau pathogenesis ntawm non-alcoholic fatty siab kab mob (NAFLD) los ntawm integrated Hi-C, Nanopore, thiab RNA sequencing, uas tau luam tawm nyob rau hauv Acta Pharmaceutica Sinica B.
Nyob rau hauv txoj kev tshawb no, High-throughput chromosome conformation capture (Hi-C), Nanopore sequencing, thiab RNA-sequencing (RNA-seq) kev soj ntsuam tau ua nyob rau hauv daim siab ntawm ib txwm thiab NAFLD nas.
Txheeb xyuas qhov kev hloov pauv hauv ntau txhiab cheeb tsam thoob plaws genome nrog rau 3D chromatin lub koom haum thiab kev hloov kho genomic, nruab nrab ntawm cov nas ib txwm muaj thiab NAFLD, thiab qhia txog cov noob caj noob ces feem ntau nrog cov kev hloov pauv no.Cov neeg sib tw hom phiaj tau txheeb xyuas hauv NAFLD, cuam tshuam los ntawm kev hloov kho caj ces thiab kev cuam tshuam ntawm lub koom haum spatial.
Cov kev tshawb pom tshiab muaj kev nkag siab txog cov txheej txheem tshiab ntawm NAFLD pathogenesis thiab tuaj yeem muab lub tswv yim tshiab rau kev kho NAFLD.
Nyemntawm nokom paub ntau ntxiv txog qhov kev kawm no.
Post lub sij hawm: Oct-30-2023