Hāʻawi ʻo BMKGENE i nā lawelawe sequencing RNA non-coding lōʻihi no ka ʻatikala "The nanoformula of zoledronic acid and calcium carbonate targets osteoclasts and reverses osteoporosis", i paʻi ʻia ma Biomaterials, ma ʻaneʻi, hoʻomohala ʻia kahi nanoplatform-HMCZP o OCs 'microenvironment-responsive nanoplatform-HMCZP.
Hōʻike ka haʻawina e ʻoi aku ka maikaʻi o ka HMCZP i ke kāohi ʻana i ka hana OC oʻo a me ka hoʻohuli ʻana i ka nalowale o ka iwi ʻōnaehana i nā ʻiole ovariectomized i hoʻohālikelike ʻia i ka lāʻau lapaʻau mua.Ua hōʻike ʻia ke kaʻina hana RNA kiʻekiʻe (RNA-seq) hiki i ka HMCZP ke hoʻoponopono i kahi pahuhopu koʻikoʻi no ka osteoporosis, tartrate-resistant acid phosphatase (TRAP), a me nā pahuhopu lapaʻau ʻē aʻe.Hōʻike kēia mau ʻike i ka hoʻohana ʻana i kahi nanoplatform naʻauao e kuhikuhi ana i nā OC he hoʻolālā hoʻohiki no ka osteoporosis therapy.
Kaomimaaneie aʻo hou e pili ana i kēia haʻawina.
Ka manawa hoʻouna: Dec-20-2023