Hāʻawi ʻo BMKGENE i nā lawelawe spatial transcriptome sequencing no ke aʻo ʻana "STEEL hiki i ka delineation kiʻekiʻe o ka spatiotemporal transcriptomic data", i paʻi ʻia ma Briefings in Bioinformatics.
Ua noi kēia noiʻi i kahi algorithm e pili ana i ka hoʻonaʻauao ʻole, Spatial Transcriptome cEll typE clustering (STEEL), ka mea e ʻike ai i nā kikowaena mai ka transcriptome spatial ma o ka clustering beads e hōʻike ana i nā moʻolelo hōʻike gene like loa a me ka mamao spatial kokoke i ke ʻano o nā kiʻi.
Hōʻike ka loiloi piha ʻana o STEEL ma nā spatial transcriptomic datasets mai ka 10X Visium platform e hōʻike ana ʻaʻole ia e hoʻokō i kahi hoʻonā kiʻekiʻe e hōʻike i nā hale maikaʻi o ka lolo ʻiole akā hiki nō hoʻi i ka hoʻohui ʻana i nā kiʻi paheʻe kikoʻī i nānā ʻia i loko o kahi nui.
Me ka holomua o nā ʻenehana transcriptome spatial, e hoʻohana nui kā mākou ala i ka ʻike domain a me ke kūkulu hou ʻana o ka gene expression atlas.
Kaomimaaneie aʻo hou e pili ana i kēia haʻawina.
Ka manawa hoʻouna: Oct-20-2023