Hāʻawi ʻo BMKGENE i nā lawelawe sequencing spatial transcriptomics no kēia noiʻi: kahi Drosophila homologue o mammalian adhesion GPCRs, i komo i nā hopena antitumor i injected oncogenic cell i nā nalo, i paʻi ʻia ma PNAS, mthl1.
I loko o kēia noiʻi ʻana, ua hoʻopiʻi ʻia nā nalo kāne makua me nā OC, a ua hana ʻia ka spatial transcriptome sequencing ma nā nalo hau.ʻO ka hoʻokomo ʻia ʻana o nā OC i loko o nā nalo kāne makua e hoʻoulu i kahi pane transcriptomic ikaika i nā lele hoʻokipa e hōʻike ana i nā ʻano genes e hoʻopili ana i nā protein bona fide G-coupled, a ma waena o ia ka mea kaulana no ka methuselah-like 1.
Ma o ka hui pū ʻana o nā hoʻololi genetic o ka mthl1 gene (nalo o ka hana a me ka overexpression o mthl1), i palapala ʻia he hopena antiproliferative kēia ʻano.Eia hou, e hōʻike i ka mthl1 kaohi i ka hōʻike ʻana o ka nui o nā genes coding no chemoreceptors a me nā genes i hoʻopili ʻia i ka hoʻoponopono ʻana i ka hoʻomohala ʻana.Hoʻoholo i nā hana pale o nā nalo e kūʻē i nā maʻi maʻi me ka ʻole o ka adaptive immunity.
Kaomi ma aneʻi e aʻo hou e pili ana i kēia haʻawina
Ka manawa hoʻouna: ʻAukake-10-2023