Ua hāʻawi ʻo BMKGENE i ka lawelawe transcriptome sequencing no ke aʻo ʻana "He cascade nanoreactor no ka hoʻonui ʻana i ka sonodynamic therapy ma ka maʻi maʻi colorectal ma o ka hoʻonui ʻana i ka ROS synergistic a me ka blockage autophagy", i paʻi ʻia ma Nano Today.
Ke manaʻo nei kēia noiʻi e hoʻomaikaʻi i ka pono antitumor o ka sonodynamic therapy (SDT) ma ka maʻi maʻi colorectal, me ka hoʻolālā ʻana i kahi nanoreactor cascade ma o ka hoʻokomo ʻana i ka sonosensitizer Ce6 a me ka autophagy inhibitor chloroquine i loko o ka homologous tumor cell membrane-modified hollow polydopamine nanocarrier i hoʻopaʻa mua ʻia me nā nanozymes platinum. (koho ʻia ʻo CCP@HP@M).
Ua hōʻoia pū ʻia nā loiloi RNA-seq i ka apoptosis a me nā ala ferroptosis i komo i ka mālama CCP@HP@M.E hāʻawi kēia cascade nanoreactor i kahi hoʻolālā hoʻohiki no ka hoʻonui ʻana i ka hoʻopau ʻana o SDT e kūʻē i nā ʻōpū ma o ka modulation o ROS a me autophagy.
Kaomimaaneie aʻo hou e pili ana i kēia ʻatikala.
Ka manawa hoʻouna: Sep-08-2023