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Nā Genetics Evolutionary
Hoʻokumu ʻia ka heluna kanaka a me ka evolutionary genetic analysis platform ma ke kumu o ka ʻike nui i hōʻiliʻili ʻia i loko o ka hui BMK R&D no nā makahiki.He mea hoʻohana pono ia no ka poʻe noiʻi ʻaʻole nui i ka bioinformatics.Hāʻawi kēia kahua i ka loiloi kumu e pili ana i ka genetics evolutionary e pili ana i ke kūkulu ʻana i nā kumulāʻau phylogenetic, linkage disequilibrium analysis, genetic diversity assessment, selective sweep analysis, kinship analysis, PCA, population structure analysis, etc.
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pōʻai-RNA
ʻO Circular RNA(circRNA) kahi ʻano o ka RNA non-coding, i ʻike ʻia i kēia manawa e pāʻani i ke kuleana koʻikoʻi i nā pūnaewele hoʻoponopono e pili ana i ka hoʻomohala ʻana, ke kū ʻana o ke kaiapuni, a me nā mea ʻē aʻe. Hoʻohui ʻia nā ʻaoʻao o ka circRNA e hana i kahi ʻano pōʻai, e hoʻopakele iā lākou mai ka ʻeli ʻana o exonuclease a ʻoi aku ka paʻa ma mua o ka hapa nui o ka RNA linear.Ua ʻike ʻia ʻo CircRNA he mau hana like ʻole i ka hoʻoponopono ʻana i ka hōʻike gene.Hiki i ka CircRNA ke hana ma ke ʻano he ceRNA, nāna e hoʻopaʻa i ka miRNA me ka hoʻokūkū, i kapa ʻia ʻo miRNA sponge.Hāʻawi ka CircRNA sequencing analysis platform i ka hoʻolālā circRNA a me ka nānā ʻana i ka ʻōlelo, ka wānana pahuhopu a me ka loiloi hui pū me nā ʻano mole RNA ʻē aʻe.
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BSA
ʻO ka paepae Bulked Segregant Analysis he hoʻokahi-ʻanuʻu maʻamau ka nānā ʻana a me ka loiloi holomua me ka hoʻonohonoho hoʻonohonoho maʻamau.ʻO ka BSA kahi ʻenehana i hoʻohana ʻia e ʻike koke i nā hōʻailona genetic pili phenotype.Aia i loko o ke kaʻina hana nui o BSA: 1. ke koho ʻana i ʻelua pūʻulu kanaka me nā ʻano ʻano kūʻē loa;2. ka hoʻohui ʻana i ka DNA, RNA a i ʻole SLAF-seq (Hoʻokumu ʻia e Biomarker) o kēlā me kēia kanaka e hana i ʻelua nui o ka DNA;3. ka ʻike ʻana i nā kaʻina like ʻole e pili ana i ka genome kuhikuhi a i ʻole ma waena, 4. wānana i nā wahi i hoʻopili ʻia e ka moho e ED a me SNP-index algorithm;5. Ka nānā 'ana a me ka ho'onui 'ana i nā genes ma nā wahi moho, a me nā mea 'ē a'e. Loa'a pū ka 'eli 'ana i ka 'ikepili me ka nānā 'ana i ka genetic marker a me ka ho'olālā kumu.
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Amplicon (16S/18S/ITS)
Hoʻokumu ʻia ka paepae Amplicon (16S/18S/ITS) me nā makahiki o ka ʻike i ka microbial diversity project analysis, i loaʻa i ka loiloi kumu maʻamau a me ka loiloi pilikino: uhi ʻia ka loiloi kumu i ka ʻike loiloi kumu o ka noiʻi microbial o kēia manawa, waiwai a piha ka ʻikepili. a hōʻike ʻia nā hopena hoʻopaneʻe ma ke ʻano o nā hōʻike papahana;He ʻokoʻa ka ʻike o ka loiloi pilikino.Hiki ke koho ʻia nā laʻana a hiki ke hoʻonohonoho maʻalahi e like me ka hōʻike loiloi kumu a me ke kumu noiʻi, e ʻike ai i nā koi pilikino.ʻO ka ʻōnaehana hana Windows, maʻalahi a wikiwiki.
