A cikin 2021, BMKGENE ya shaida 31 De novo genome binciken ya sami nasarar buga shi a cikin manyan mujallu masu tasiri tare da jimlar abubuwan tasiri sama da 320. 15 daga cikin labaran an haɗa su tare 4 daga cikinsu an haɗa su azaman marubutan farko ta BMKGENE.
Dama bayan farkon shekara ta 2022, an riga an sami labaran bincike guda biyu da aka buga a mujallar "Natural Genetics" da "Tsarin Kwayoyin Halitta" bi da bi.Su ne, "Haplotypes biyu daban-daban daga genome na heterozygous lychee mai girma yana ba da shawarar abubuwan da suka faru na gida masu zaman kansu don farkon da kuma ƙarshen balagagge cultivars" (Binciken Lychee genome, wanda Kwalejin Horticulture, Jami'ar Aikin Noma ta Kudancin China, da masu haɗin gwiwar kimiyya, aka buga a kan Halittar Halitta. ), da kuma "Jerin Genome na nau'in Sitopsis guda biyar na Aegilops da kuma asalin alkama na polyploid B-subgenome" (Genom na nau'in Sitopsis biyar, wanda ƙungiyar bincike ta Farfesa Bao Liu na Jami'ar Al'ada ta Arewa maso Gabas ta gudanar.).Za mu kuma sake duba waɗannan labaran biyu kuma mu raba wa masu karatunmu.
Yanzu, bari mu kalli ingantattun labaran bincike da aka buga akan 2021 wanda BMK tare da haɗin gwiwar kayan aikinmu suka rubuta.
Plant Genome - Nasara akan nau'ikan nau'ikan iri-iri.
1.A high quality-genome taro yana ba da haske halaye na hatsin rai genomic halaye da kuma agronomically muhimmanci kwayoyin.
Cibiyar Haɗin gwiwa: Jami'ar Aikin Noma ta Henan
Jarida: Halitta Halitta
Sakamakon Tasiri: 38.31
A cikin wannan aikin, an jera nau'in nau'in hatsin rai na Weining Rye.Ƙungiyoyin da aka haɗa (7.74 Gb) sun kai kashi 98.47% na ƙididdigan girman kwayoyin halitta (7.86 Gb), tare da 93.67% na contigs (7.25 Gb) da aka sanya wa chromosomes bakwai.Abubuwan maimaitawa sun ƙunshi 90.31% na kwayoyin halittar da aka haɗa.Ƙarin nazari na taron Weining ya ba da sabon haske game da kwafi na nau'in kwayoyin halitta da tasirin su akan kwayoyin sitaci biosynthesis, tsarin jiki na hadaddun prolamin loci, fasalin fasalin halittar da ke da alaƙa da yanayin farko da kuma yankunan chromosomal da ke hade da gida da kuma loci a cikin hatsin rai.Wannan jeri na kwayoyin halitta yayi alƙawarin haɓaka nazarin kwayoyin halitta da kiwo a cikin hatsin rai da albarkatun hatsi masu alaƙa.
2.Rose ba tare da prickle ba: fahimtar genomic da ke da alaƙa da daidaitawar danshi
Wuraren Haɗin Kai: Cibiyar Kunming na ilimin dabbobi, Kwalejin Kimiyyar Sinawa
Jarida: Binciken Kimiyya na Ƙasa
Sakamakon Tasiri: 17.273
A cikin wannan aikin, samfuran 'Basye's Thornless' (BT, cultivar mara amfani na Rosa wichuraiana), 'Old Blush' (OB, wanda ya kafa genotype a cikin gidan fure), an tattara su F1 hybrids da BCF1.Kuma an ƙirƙiri babban taro na genome don gano abubuwan da ke da alaƙa da ci gaban prickle.Girman genome shine kusan 530.6 Mb.Don tabbatar da ingancin genome ɗin da aka haɗa, bincike kamar kwatancen taswirar kwayoyin halitta, BUSCO, NGS yana karanta sake haduwa, kwatantawa da OB haplotype, tsarin sarrafa ƙimar kuskuren tushe da ƙididdigar ƙimar ƙimar Majalisar LTR mai faɗi (LAI=20.03).Wannan bincike ya bayyana hadadden tsarin gado da tsarin tsari na karan prickles kuma ya samar mana da tushe da albarkatu don nazarin ilimin halittar fure da alamomin kwayoyin halitta masu alaƙa da muhimman halaye.
3. Gabaɗaya-Genome jerin Allopolyploids da aka haɗa a cikin Cucumis Ya Bayyana Haƙiƙa cikin Juyin Halitta na Allopolyploidization.
Cibiyar Haɗin Kai: Jami'ar Aikin Noma ta Nanjing
Jarida: Advanced Science
Sakamakon Tasiri: 16.801
Wannan binciken ya ba da rahoton babban ingancin genome na allotetraploid na roba da aka samu ta hanyar amfani da haɗin kai tsakanin kokwamba (C. sativus, 2n = 14) da nau'in dangi na daji (C. hystrix, 2n = 24) da kwafin chromosome na gaba, wanda shine farkon na farko. allopolyploid roba mai cikakken jeri.Taro na genome ya yi amfani da tsarin aikin "PacBio+BioNano+Hi-C+Ilumina", ya haifar da girman genome na 530.8Mb da contig N50 = 6.5Mb.An sanya karatun zuwa 19 pseudochromosomes da subgenomes.Sakamakon ya nuna cewa haɓakawa, maimakon kwafin kwayoyin halitta, yana haifar da yawancin canje-canjen kwayoyin halitta a cikin nau'ikan kwayoyin halitta da na cp.Ya ba da shawarar cewa tsayayyen heterozygosity yana ba da C. × hytivus tare da haɓaka haɓakar damuwa.Sakamakon yana ba da sabbin fahimta game da juyin halittar polyploidy shuka kuma yana ba da dabarun kiwo don amfanin gona na gaba.
4.Comparative Genome Yana Nazari Haskaka Tsakanin Tsakanin Tsakanin Tsarin Halittar Halittar Halittar Halitta da Tsarin Juyin Halitta na 3D Genomic Folding a Auduga
Cibiyar Haɗin Kai: Jami'ar Aikin Noma ta Huazhong
Jarida: Halittar Halitta da Juyin Halitta
Sakamakon Tasiri: 16.242
Wannan aikin ya yi amfani da Nanopore Sequencing don harhada kwayoyin halittar nau'in auduga guda uku wato: Gossypium rotundifolium (K2, genome size = 2.44Gb, contigN50 = 5.33Mb), G. arboreum (A2, genome size = 1.62Gb, contigN.50), da kuma 111M = G. raimondii (D5, genome size = 0.75Gb, contigN50 = 17.04 Gb).Fiye da kashi 99% na dukkanin kwayoyin halitta guda uku an tattara su ta hanyar Hi-C.Sakamakon binciken BUSCO shine 92.5%, 93.9% da 95.4% bi da bi.Duk waɗannan lambobi sun nuna cewa genomes ɗin taro guda uku suna da ma'ana - daraja.Kwatancen kwatankwacin genome ya rubuta cikakkun bayanai na ƙayyadaddun ƙayyadaddun layin TE wanda ke ba da gudummawa ga manyan bambance-bambancen girman genome.Wannan binciken yana ba da haske game da rawar da ke tattare da yaduwar kwayar halitta ta transposon a cikin juyin halittar chromatin mafi girma a cikin tsirrai.
5.Chromosome-sikelin taro da bincike na biomass amfanin gona Miscanthus lutarioriparius genome
Wuraren Haɗin gwiwa: Cibiyar CAS don Ƙwarewa a cikin Kimiyyar Tsirrai
Jarida: Sadarwar yanayi
Sakamakon Tasiri: 14.912
Wannan aikin ya ba da rahoton taro na sikelin chromosome na Miscanthus lutarioriparius genome ta hanyar haɗa jerin abubuwan Oxford Nanopore da fasahar Hi-C.Taron 2.07Gb ya ƙunshi 96.64% na kwayoyin halitta, tare da N50 na 1.71 Mb.Kimanin kashi 94.30% na jimlar jeri an tattara su zuwa 19 pseudochromosomes.Ta hanyar kwatanta tare da jerin BAC, kimantawa na LAI, kimantawa na BUSCO, sake haɗuwa tare da bayanan NGS, sake tattara bayanan da aka rubuta, an ƙididdige kwayoyin halitta a matsayin babban inganci da ci gaba.An tabbatar da asalin Alloteraploid na M. lutarioriparius ta amfani da maimaita tauraron dan adam centromeric.Kwafin kwayoyin halittar Tandem na M. lutarioriparius suna aiki ne waɗanda aka wadatar ba kawai cikin sharuɗɗan da suka danganci amsa damuwa ba, amma biosynthesis na bangon tantanin halitta.Kwafin Halittu mai yiwuwa suna taka rawa a cikin C4 photosynthesis kuma suna ba da gudummawa ga Miscanthus C4 photosynthesis a ƙananan zafin jiki.Binciken ya ba da mahimman bayanai don nazarin tsire-tsire na perennial.
6.A matakin-chromosome Camptotheca acuminata genome taro yana ba da haske game da asalin juyin halitta na camptothecin biosynthesis.
Cibiyar Haɗin gwiwa: Jami'ar Sichuan
Jarida: Sadarwar yanayi
Sakamakon Tasiri: 14.912
Wannan aikin ya ba da rahoton babban inganci, matakin-chromosome-level C. acuminata genome taro, tare da girman genome na 414.95Mb da ci gaba da N50 1.47Mb.Mun gano cewa C. acuminata ya sami kwafi mai zaman kansa gabaɗaya-genome kuma yawancin kwayoyin halitta da aka samo daga gare ta suna da alaƙa da biosynthesis na camptothecin.Bambance-bambancen aiki na kwayoyin LAMT da ingantaccen juyin halitta na kwayoyin SLAS guda biyu, saboda haka, duka biyu sun ba da gudummawa sosai ga biosynthesis na camptothecin a cikin C. acuminata.Sakamakon ya jaddada mahimmancin babban taro na kwayoyin halitta don gano canje-canjen kwayoyin halitta a cikin asalin juyin halitta na metabolite na biyu.
7.Allele-defined genome yana bayyana bambancin bialelic yayin juyin halittar rogo
Wuraren Haɗin Kai: Kwalejin Kimiyyar Noma ta kasar Sin
Jarida: Shuka Kwayoyin Halitta
Sakamakon Tasiri: 13.162
Wannan aikin ya haɗa nau'in kwayar halitta na rogo tare da contigN50 1.1Mb ta amfani da dandali na sequencing na Pacific Biosciences (PacBio).Bayan kimantawa ta BUSCO, fihirisar LAI, da taswirar kwayoyin halitta mai girma, an tabbatar da kwayar halittar da aka taru a matsayin-daraja.An gano yankunan da aka sake yin amfani da su kuma an dasa su a kan pseudochromosomes 18 ta amfani da hanyoyin Hi-C.Wannan babban inganci da ƙayyadaddun ƙayyadaddun kwayoyin halitta na rogo yana da mahimmanci wajen gano bambance-bambancen bi-alleles akan chromosomes masu kama da juna, yana ba da damar bincika bambance-bambance da bayyana rinjaye na bi-allele da tushen ƙarfin tuƙi na juyin halitta.Ya sauƙaƙa sabbin dabarun kiwo a cikin rogo da sauran amfanin gona masu yawan gaske.
8.Genomic basira cikin sauri girma na paulownias da samuwar Paulownia tsintsiya mayu.
Haɗin gwiwa Facility: Henan Agricultural University
Jarida: Shuka Kwayoyin Halitta
Sakamakon Tasiri: 13.162
Wannan aikin ya haɗu da ingantaccen ƙwayar cuta ta Paulownia fortunei, 511.6 Mb a girman, tare da 93.2% na jerin abubuwan an haɗa su zuwa 20 pseudochromosomes.Ana samun ingantacciyar ingancin hoto ta hanyar haɗa C3 photosynthesis da hanyar crassulacean acid metabolism, wanda ƙila ya ba da gudummawa ga al'adar girma mai saurin gaske na bishiyoyin paulownia.Ƙarin tsarin kwayoyin halitta na PaWB phytoplasma, haɗe tare da nazarin aiki, ya nuna cewa mai tasiri PaWB-SAP54 yana hulɗa kai tsaye tare da Paulownia PfSPLa, wanda hakan ya haifar da lalacewar PfSPLa ta hanyar tsaka-tsakin ubiquitin kuma yana haifar da samuwar tsintsiya.Bayanan sun ba da haske mai mahimmanci game da ilimin halitta na paulownias da tsarin tsari don samuwar PaWB.
Halittar dabba - Zurfafa fahimtar juyin halittar jinsin
1.Gomenom na Nautilus pompilius yana haskaka juyin halittar ido da biomineralization
Wurin Haɗin Kai: Cibiyar Nazarin Teku ta Kudancin China, CAS
Jarida: Halitta Halitta & Juyin Halitta
Sakamakon Tasiri: 15.462
Wannan aikin ya gabatar da cikakkiyar kwayar halitta ga Nautilus pompilius.Yana da mafi ƙarancin genome a cikin jerin cephalopods, wanda shine 730.58Mb tare da contigN50 = 1.1Mb.Sakamakon kimantawa na BUSCO shine 91.31%.Haɗe tare da transcriptome, proteome, jinsin iyali da kuma nazarin halittu, wannan kwayar halitta ta ba da mahimmancin tunani game da sababbin abubuwa na cephalopod, kamar ido na pinhole da biomineralization.Binciken ya nuna cewa lalacewa akan cikar tarin kwayoyin halittar Hox na iya kasancewa da alaƙa da bacewar harsashi na Mollusks.Mahimmanci, sabbin abubuwa masu yawa da suka haɗa da hasarar kwayoyin halitta, ƙanƙancewa mai zaman kanta da faɗaɗa takamaiman iyalai na jinsin halittu da hanyoyin sadarwar su masu alaƙa da yuwuwar haifar da haɓakar idon nautilus pinhole.Nautilus genome ya zama wata hanya mai mahimmanci don sake gina yanayin juyin halitta da sabbin abubuwa na kwayoyin halitta waɗanda ke siffanta cephalopods na baya.
2.Seadragon genome bincike yana ba da haske game da nau'in nau'in sa da kuma wurin ƙayyade jima'i
Wurin Haɗin Kai: Cibiyar Nazarin Teku ta Kudancin China, CAS
Jarida: Ci gaban Kimiyya
Sakamakon Tasiri: 14.132
Wannan aikin de novo-jerin kwayoyin halittar maza da mata na ruwan teku na gama-gari (Phyllopteryx taeniolatus) da nau'in da ke da alaƙa da shi, da alligator pipefish (Syngnathoides biaculeatus).Girman genome na Phyllopteryx taeniolatus shine ~ 659 Mb (♂) da ~ 663 Mb (♀), tare da contigN50 na 10.0Mb da 12.1mb.Girman genome na Phyllopteryx taeniolatus shine 637 Mb (♂) da ~ 648 Mb (♀), tare da contigN50 na 18.0Mb da 21.0Mb.Ta hanyar nazarin phylogenetic, ruwan teku na gama-gari da kifin alligator 'yar'uwar taxon Syngnathinae ne, kuma sun bambanta a kusa da 27.3 Ma da suka wuce.Bayanan bayanan rubutu daga sabon salo na juyin halitta, abubuwan da ke kama da ganye, sun nuna cewa an haɗa jerin kwayoyin halittar da ke da hannu wajen haɓaka fin tare da wadatar rubutun don yuwuwar gyara nama da ƙwayoyin kariya na rigakafi.Jima'i mai sanyawa-ƙayyade wurin da ke ɓoye wani takamaiman jinsin amhr2y na namiji wanda aka raba ta ruwan teku da alligator pipefish.Wannan aikin ya ba da shaida mai mahimmanci don nazarin juyin halitta daidaitacce.
Lokacin aikawa: Satumba-19-2022