JUYIN HALITTA
yanayi
SADARWA
Jeren kwayoyin halitta suna bayyana hanyoyin tarwatsa duniya kuma suna ba da shawarar daidaitawar kwayoyin halitta a cikin juyin halittar dokin teku.
PacBio |Illumina |Hi-C |WGS |Bambancin Halitta |Tarihin Alkaluma |Tsarin Halitta
Biomarker Technologies ne suka samar da tsarin Pacbio, taron genome de novo da sabis na annotation.
Karin bayanai
1.A high quality-chromosome-level seahorse (Hippocampus erectus) genome tare da contig N50 na 15.5 Mb aka samu.
2.Jimillar kwayoyin halitta 358 daga cikin nau'ikan dokin teku guda 21 na duniya an sake su.
3.Seahorses sun samo asali a cikin marigayi Oligocene kuma an gano hanyoyin da suka biyo bayan mulkin mallaka na duniya kuma suna da alaƙa da canjin yanayi a cikin magudanar ruwa da kuma buɗewar tekun paleotemporal.
4.Tsarin kwayoyin halitta na maimaituwar "kashin kashin kasusuwa" phenotype na daidaitawa yana da alaƙa da sauye-sauye masu zaman kansu a cikin maɓallin ci gaba mai mahimmanci.
5.Rafting via teku igiyoyin rama domin matalauta tarwatsa da kuma saurin karbuwa sauƙaƙe colonizing sabon mazauninsu.
Nasarorin da aka samu
Hoto na 1 Bambance-bambancen kwayoyin halitta da alakar halittar dokin teku 358
aWuraren samfurin yanki don samfurin dawakan teku tare da tsarin bambancin nucleotide (π) na nau'in dokin teku 21 a cikin chromosomes 22.b Maƙwabtan bishiyar da aka gina tare da SNPs masu faɗin genome na dokin teku 358.Alamun fil ɗin wuri a (a) da bangon reshe a (b) sun dace da juna.
Hoto 2 Mallaka da tarihin alƙaluma na dokin teku
aBishiyar Phylogenetic da kiyasin lokacin rarrabuwar kawuna don nau'ikan dokin teku 21.Kaurin layin reshe yayi daidai da ƙididdigar girman yawan jama'a (Ne) kuma launuka suna nuna zuriya daban-daban.Alamomin I-III suna nuna maki daidaitawa.b-d Hanyoyi na mulkin mallaka (kibiyoyi masu launi) na dokin teku dangane da lokacin rarrabuwa, rarrabawa, abubuwan da suka faru, da igiyoyin ruwa (fararen kibiyoyi).b Tsarin tsibiri na Indo-Australian shine cibiyar asalin (alamar ja) na zuriyar Hippocampus kafin dawakin teku ya bambanta kuma su watse a duniya 18-23 Ma.c Seahorses da farko sun mamaye Tekun Atlantika ta hanyar bude Tethyan Seaway, wanda, bayan rufe shi (Wakilin Tasha a lokacin 7 – 13 Ma), ya raba wannan zuriyar Tethyan daga danginta na Tekun Indiya.Ƙarshen, daga baya ya bambanta da sauri (alamar rawaya) a cikin Tekun Arabiya, ya kafa cibiyar na biyu na haɓaka dokin teku.d Wani abin da ya faru na mamayar dawakin teku na biyu na Tekun Atlantika ya faru ne daga Tekun Indiya kimanin 5Ma ta hanyar wucewa ta Afirka ta Kudu, kuma daga ƙarshe ya isa Gabashin Tekun Pasifik ta hanyar tekun Panama da ke buɗe kusan 3.6 Ma.
Hoto 3 Gudun Gene da sauye-sauye a cikin ingantaccen girman yawan jama'a
aAn gano kwararar kwayoyin halitta tsakanin nau'ikan da ke zaune a Kudancin Tekun Atlantika.Ana nuna kwararar Gene a kusa da fararen layukan kamar yadda G-PhoCS ya rage yawan ƙaura.Kauri da alkiblar kibiyoyi sun yi daidai da ƙima da alkiblar kwararar kwayoyin halitta, bi da bi.b Canje-canje a cikin ingantaccen girman yawan jama'a ta PSMC.Axis x yana wakiltar lokaci a cikin shekaru kafin yanzu yayin da y axis yana wakiltar ingantaccen girman yawan jama'a.An tsara ginshiƙi musamman bisa ga rarrabawar ƙasa ga kowane nau'in nau'in da ke da wuraren rarraba daban-daban.c Canjin yanayin teku a cikin shekaru miliyan 1 da suka gabata a cikin mita 33.Layin rawaya yana nuna ƙarshen tsaka-tsakin tsaka-tsakin tsaka-tsakin duniya yayin da inuwar cyan ke nuna iyakar lokacin glacial na ƙarshe.
Hoto 4 Juyin Juyin Halitta.
aHagu, Bishiyar nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in halitta) yana nuna juyin halitta na kashin baya a cikin dawakan teku.Tsawon reshe yana nuna adadin maye gurbin kowane rukunin yanar gizo.An ba da haske nau'in dokin teku guda huɗu da shuɗi.Manyan rassan sun yi daidai da mafi girman ƙimar maye gurbin da ba a san su ba (dN/dS) don ƙwayar halittar bmp3.Canonical da kuma an yi gwajin Kreitman (MKT) don jinsin 'yar'uwar da ba ta nuna bambanci ba ta hanyar ƙimar piel da ja font, bi da bi.Dama, kwatankwacin maye gurbin amino acid a cikin furotin bmp3, polymorphic da ƙayyadaddun musanya a cikin dokin ruwa mai kaifi ana nuna su tare da da'irar ja da shuɗi, bi da bi.b Rarraba darajar dN/dS a cikin bmp3 a cikin dawakan ruwan teku idan aka kwatanta da nau'in maras kashin baya.c Juyin halitta mai zaman kansa a cikin bishiyar phylogenetic da aka sake ginawa don sunadarin da bmp3 ya rufa masa asiri.d Duka-duka a cikin yanayin haɓakar bmp3 a cikin Hippocampus erectus.
Magana
Li C et al.Jeren kwayoyin halitta suna bayyana hanyoyin tarwatsa duniya kuma suna ba da shawarar daidaitawar kwayoyin halitta a cikin juyin halittar dokin teku.Na Komun.2021 Fabrairu 17; 12 (1): 1094.
Labarai da Labarai yana da niyyar raba sabbin maganganu masu nasara tare da Biomarker Technologies, ɗaukar sabbin nasarorin kimiyya gami da fitattun dabarun da aka yi amfani da su yayin binciken.
Lokacin aikawa: Janairu-06-2022