Bincika sifofin maganganun kwayoyin halitta a wurin asali na kwayoyin halitta yana da mahimmanci don fahimtar nau'ikan da ayyukan sel.Koyaya, hanyoyin bincike na kwafin sararin samaniya na yanzu suna da iyaka kamar ƙarancin fitarwa ko ƙarancin ƙuduri.BMKMANU S1000 Spatial Chip, wanda BMKMANU ya haɓaka, zai iya gano bayanan bayanin yanayin halittar a cikin cikakkun sassan nama a ƙudurin ƙaramin salula, yana ba da damar fassarar tsarin nama mara kyau.
Shirya don dandana sabon samfurin mu!Don murnar sake shi, muna bayar da na musammanSayi Hudu Samu Daya Kyautagabatarwa na ɗan lokaci kaɗan kawai.
Abubuwan Samfur
BMKMANU S1000 sarari guntu da matching reagent kit sun hada da:
1) Kit ɗin Inganta Nama, mai ɗauke da reagents don inganta nama (mafi kyawun bincike na lokaci don lalata nama).
2) Kit ɗin Maganar Gene, mai ɗauke da reagents don ɗaukar mRNA a cikin yankan nama don shirye-shiryen ɗakin karatu na gaba da jeri.
3) Kit ɗin farawa: Ya haɗa da adaftar thermostatic da mai raba maganadisu mai kwafi.
Ƙa'idar Fasaha
Guntu yana dogara ne akan micropores da microbeads, kuma ana iya kama mRNA a cikin wurin ta hanyar Oligo akan microbeads.Oligo ya ƙunshi sassa huɗu: Read1, Spatial Barcode, UMI, da Poly(dT)VN.Bayan an haɗe nama zuwa guntu, ana fitar da mRNA daga nama ta hanyar enzyme permeabilisation.Tunda yawancin ƙarshen mRNA 3' suna da wutsiya ta Poly-A, Oligo ya kama su tare da Poly(dT) VN.Bayan haɓakawa na RT-PCR da cDNA, shirye-shiryen ɗakin karatu da jeri, ana samun gano matsayin sarari ta hanyar Barcode.Wannan yana ba da damar nazarin maganganun kwayoyin halitta a cikin wurare masu sarari da nau'in nama.
Amfanin Samfur
Aikace-aikace
Ana iya amfani da shi ga mafi yawan wuraren bincike na ilimin halitta da na likita, ciki har da ƙari, cututtuka, rigakafi, da ilmin halitta na ci gaba, yana taimakawa wajen cimma sababbin ci gaba a cikin waɗannan fannoni tare da nazarin sararin samaniya a ƙudurin subcellular.
● Tumor da Cuta:
Bambance-bambancen sararin samaniya da microenvironment na ciwace-ciwace da cututtuka
Farko da ci gaban ciwace-ciwace da cututtuka
Maganin amsawar ciwace-ciwace da cututtuka
●Biology na Ci gaba
Spatiotemporal atlas na gabobin
Hanyoyin sarrafa kwayoyin halitta yayin haɓakawa
●Masanin damuwa
Amsar damuwa ta biotic
Amsar damuwa na Abiotic
●Immunology
Amsar rigakafi a cikin dashen gabobin jiki
Hanyoyin rigakafi na ciwace-ciwacen daji da cututtuka
Pathogenesis na cututtuka na autoimmune
● Nazarin juriya na miyagun ƙwayoyi
Hanyoyin juriya na miyagun ƙwayoyi
Bincike da haɓaka sababbin magunguna
Cases da Bayanan Demo
BMKMANU S1000 an tabbatar da aiki a cikin ɗaruruwan lokuta a cikin nau'ikan nama daban-daban.
