BMKGENE ya ba da sabis na jeri na cikakken tsayi don wannan binciken: Cikakkun bayanan bayanan da aka yi na lymphocytes suna amsawa ga IFN-γ yana nuna amsawar rigakafi ta Th1 a cikin flounder (Paralichthys olivaceus), wanda aka buga a cikin Kifi & Shellfish immunology.
A cikin wannan binciken, an gudanar da cikakken jerin abubuwan da aka kwatanta da su don nazarin kwayoyin halitta da aka bayyana (DEGs) da kuma hanyoyin sigina a cikin IFN-γ da ke motsa lymphocytes na flounder (Paralichthys olivaceus), Th1 da Th2 bambance-bambancen sel sun sami wadata sosai daga DEGs, kuma kwayoyin halittar da ke cikin hanyar bambance-bambancen cell Th1 an daidaita su kuma an tabbatar da su.Dangane da haka, an bincika bambance-bambance a kan kwayoyin halittar Th1 cell bambance-bambancen kwayoyin halitta da kuma CD4 + sel bayan IFN-γ ƙarfafawa, sakamakon ya tabbatar da cewa CD4 + T lymphocytes ya karu sosai bayan IFN-γ ƙarfafawa, tare da kwayoyin halitta takwas masu mahimmanci na haɓakawa da kuma ƙara yawan maganganun T-bet a cikin lymphocytes.
A ƙarshe, sakamakon ya bayyana ƙaddamar da IFN-γ akan amsawar rigakafi na nau'in Th1, yana ba da ra'ayi na sabon labari don bambanta CD4+ T lymphocytes a cikin teleost.
Dannanandon ƙarin koyo game da wannan binciken.
Lokacin aikawa: Oktoba-30-2023