BMKGENE ya ba da sabis na jeri na fassarar sararin samaniya don wannan binciken: yuwuwar Drosophila homologue na mammalian adhesion GPCRs, yana shiga cikin halayen antitumor zuwa allurar ƙwayoyin oncogenic a cikin kwari, wanda aka buga a PNAS, mthl1.
A cikin wannan binciken, an yi wa manyan kwari maza allura tare da OCs, kuma ana aiwatar da jerin bayanan sararin samaniya akan ƙudaje masu daskararre.Allurar OCs a cikin kudaje maza na manya yana haifar da amsa mai ƙarfi a cikin ƙudaje masu masaukin baki waɗanda ke nuna musamman kwayoyin halittar da ke ɓoye sunadaran G-coupled, wanda daga cikinsu gene don methyl-like 1 ya shahara.
Ta hanyar haɗakar manipulations na kwayoyin halittar mthl1 (asarar aiki da wuce gona da iri na mthl1), an rubuta cewa lallai wannan kwayar halitta tana da tasirin antiproliferative.Bugu da ari, nuna cewa mthl1 yana sarrafa maganganun adadi mai yawa na kwayoyin halitta don chemoreceptors da kwayoyin halitta da ke cikin tsarin ci gaba.Yanke hanyoyin kariya na kwari da ciwace-ciwace a cikin rashin rigakafi na daidaitawa.
Danna nan don ƙarin koyo game da wannan binciken
Lokacin aikawa: Agusta-10-2023