BMKCloud Log in
条形 banner-03

Kayayyaki

Kwatancen Genomics

Kwatankwacin ilimin genomics a zahiri yana nufin kwatanta cikakken jerin kwayoyin halitta da sigar nau'ikan nau'ikan nau'ikan nau'ikan.Wannan horon yana nufin bayyanar da juyin halittar nau'in halitta, aikin kwayoyin halitta, tsarin sarrafa kwayoyin halitta a matakin kwayoyin halitta ta hanyar gano tsarin tsari da abubuwan da aka kiyaye ko bambanta a cikin nau'ikan nau'ikan daban-daban.Nazari na kwatankwacin ilimin genomics na yau da kullun ya haɗa da nazari a cikin dangin jinsin halitta, haɓakar juyin halitta, kwafin kwayoyin halitta gabaɗaya, matsa lamba, da sauransu.


Cikakkun Sabis

Sakamakon Demo

Nazarin Harka

Amfanin Sabis

1 Comparative-genomics

● Cikakken fakitin nazari, yana ƙunshe da bincike takwas da ake buƙata

● Babban dogaro a cikin bincike tare da cikakken bayani da sauƙin fahimta akan sakamako

● Ƙirar da aka tsara da kyau don bugawa

● Ƙwararrun ƙwararrun ƙungiyar bioinformatics suna cika buƙatun bincike na keɓaɓɓu daban-daban

● Gajeren lokacin juyawa tare da daidaito mafi girma a cikin bincike

● Ƙwarewa mai yawa tare da shari'o'in nasara sama da 90 tare da tarin tasirin tasirin da aka buga sama da 900

Ƙayyadaddun Sabis

Kiyasin lokacin juyawa

Yawan nau'in

Yin nazari

30 kwanakin aiki

6-12

Tarin iyali

Fadada iyali da ƙanƙancewa

Gina bishiyar phylogenetic

Ƙimar lokacin rarrabuwar kawuna (ana buƙatar daidaitawar burbushin halittu)

Lokacin shigar LTR (Na tsire-tsire)

Kwafin kwayoyin halitta gaba daya (Na tsirrai)

Matsin zaɓi

Synteny bincike

Binciken bioinformatics

● Iyalin Halittu

● Physogenetics

● Lokacin rarrabuwa

● Zaɓin matsa lamba

● Nazarin synteny

流程图Comparative Genomics

Samfuran Bukatun da Bayarwa

Samfuran Bukatun:

Nama ko DNA don jerin kwayoyin halitta da haɗuwa

Don Tissue

Nau'o'i

Nama

Bincike

Farashin CCS

Dabba

Visceral nama

0.5 ~ 1 g

3.5g

Naman tsoka

5.0 g

≥ 5.0ml

Jinin dabbobi masu shayarwa

0.5 ml na ruwa

Jinin kaji/Kifi

Shuka

Fresh Leaf

1 ~2g ku

5.0 g

 

Petal/Stem

1 ~2g ku

≥ 10.0 g

 

Tushen/Iri

1 ~2g ku

≥ 20.0 g

Kwayoyin halitta

Tantanin halitta

-

1 x 108

Bayanai

Fayilolin jerin kwayoyin halitta (.fasta) da fayilolin annotation (.gff3) na nau'ikan nau'ikan da ke da alaƙa

Gudun Aikin Sabis

Misalin QC

Gwajin ƙira

samfurin bayarwa

Samfurin bayarwa

Shirye-shiryen Laburare

Gina ɗakin karatu

Jeri

Jeri

Binciken bayanai

Binciken bayanai

Bayan Sabis na siyarwa

Bayan-sayar da sabis


  • Na baya:
  • Na gaba:

  • *Sakamakon demo da aka nuna anan duk daga kwayoyin halittar da aka buga tare da Biomarker Technologies

    1.LTR saka kimar lokaci: Hoton ya nuna keɓantaccen rarraba bimodal a cikin lokutan saka LTR-RTs a cikin nau'in hatsin rai na Weining, idan aka kwatanta da sauran nau'ikan.Kololuwar kwanan nan ta bayyana kusan shekaru miliyan 0.5 da suka wuce.

    3LTR-lokacin saka-ƙimar-a-Weining-rye

    Li Guang et al.,Halitta Halitta, 2021

     

     

    2. An samo irin nazarin kwayar halitta akan chayote (Sechium Edule): ta hanyar nazarin nau'ikan mutane 13 a cikin dangin Ginire, an gano cewa Annaguua).Chayote da aka samo daga gourd maciji a cikin kusan 27-45 Mya da dukan kwayoyin halitta (WGD) an lura dasu a cikin chayote a cikin 25± 4 Mya, wanda shine taron WGD na uku a cikin cucuibitaceae.

    4 phylogenetic-itace-na-chayote

    Fu A da al.,Binciken Horticulture, 2021

     

     

    3.Synteny analysis: Wasu kwayoyin halittar da ke da alaƙa da phytohormones a cikin haɓakar 'ya'yan itace an samo su a cikin chayote, gourd maciji da squash.Dangantaka tsakanin chayote da squash ya ɗanɗana sama da na tsakanin chayote da gourn maciji.

    4 phylogenetic-itace-na-chayote

    Fu A da al.,Binciken Horticulture, 2021

     

     

    4.Gene bincike na iyali: KEGG haɓakawa akan haɓakar dangin iyali da raguwa a cikin G.thurberi da G.davidsonii genomes sun nuna cewa kwayoyin halitta na steroid biosynthesis da brassinosteroid biosynthesis sun haɓaka.

    4 phylogenetic-itace-na-chayote

    Yang Z et al.,BMC Biology, 2021

     

     

    5.Dukkan nazarin kwafi na genome: 4DTV da nazarin rarraba Ks sun nuna duk taron kwafi na genome.Kololuwa na intraspecies da aka nuna abubuwan da suka dace.Kololuwar interspecies an nuna abubuwan da suka faru ta musamman.Nazarin ya nuna cewa yana kwatanta tare da sauran jinsunan da ke da alaƙa da uku, O. Europaea ya bi babban sikelin grale da kwanan nan.

    4 phylogenetic-itace-na-chayote

    Rao G et al.,Binciken Horticulture, 2021

    BMK Case

    Rose ba tare da prickle ba: fahimtar kwayoyin halitta da ke da alaƙa da daidaitawar danshi

    Buga: Binciken Kimiyya na Ƙasa, 2021

    Dabarun tsarawa:

    'Basye'sMara ƙaya(R.Wichurainangenome:
    Kimanin93 X PacBio + kusan.90 X Nanopore + 267 X Illumina

    Sakamako mai mahimmanci

    1.An gina babban ingancin R.wichuraiana genome ta hanyar amfani da dabarun da aka dade ana karantawa, wanda ke samar da taro na 530.07 Mb (Kimanin girman genome ya kusan 525.9 Mb ta hanyar cytometry kwarara da 525.5 ta hanyar binciken genome; Heterozygosity yana kusa da 1.03%).BUSCO ta kiyasta maki 93.9%.Idan aka kwatanta da "Tsohuwar blush" (haploOB), inganci da cikar wannan kwayar halitta an tabbatar da su ta hanyar daidaitattun tushe guda ɗaya da ma'aunin taro na LTR (LAI=20.03).R.wichuraiana genome ya ƙunshi ƙwayoyin furotin 32,674.

    2.Multi-omics haɗin gwiwa bincike, wanda ya ƙunshi kwatancen genomics, transcriptomics, QTL bincike na yawan kwayoyin halitta, ya bayyana mahimmin ƙira tsakanin R. wichuraiana da Rosa chinensis.Hakanan, bambancin magana na kwayoyin halitta masu alaƙa a cikin QTL ana iya danganta su da ƙirar tushe.

    7KEGG-haɓaka-kan-gene-family-family-da-kwagi

    Kwatankwacin ilimin genomics anaysis tsakanin Basye;s Thornless da Rosa chinensis ciki har da nazarin synteny, gungu na iyali, fadadawa da bincike na ƙanƙancewa, ya bayyana ɗimbin bambance-bambance, waɗanda ke da alaƙa da mahimman halaye a cikin wardi.Faɗawa na musamman a cikin dangin NAC da FAR1/FRS ana iya danganta su da juriya ga tabo baƙar fata.

    81 Kwatanta-genomics-bincike-tsakanin-BT-da-OB 82 Kwatanta-genomics-bincike-tsakanin-BT-da-OB 83 Kwatanta-genomics-bincike-tsakanin-BT-da-OB

    Binciken kwatankwacin genomics tsakanin BT da haploOB genomes.

    Magana

    Zhong, M., da dai sauransu."Rose ba tare da prickle ba: fahimtar genomic da ke da alaƙa da daidaitawar danshi"Binciken Kimiyya na Ƙasa, 2021;, nnwab092.

    samun zance

    Ku rubuta sakonku anan ku aiko mana

    Aiko mana da sakon ku: