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Featured Publication – Dicer-2 mutations in Aedes aegypti cells lead to a diminished antiviral function against Rift Valley fever virus and Bunyamwera virus infection
The article published in Journal Of General Virology, Dicer-2 mutations in Aedes aegypti cells lead to a diminished antiviral function against Rift Valley fever virus and Bunyamwera virus infection. Mosquitoes are known to transmit different arthropod-borne viruses belonging to various virus fami...Read more -
Featured Publication – Tracing the evolutionary and genetic footprints of atmospheric tillandsioids transition from land to air
Exciting news! Another breakthrough application of BMKMANU Spatial Transcriptomics Technology in the plant domain! Our client’s pioneering study, published in Nature Communications on November 6th, titled “Tracing the evolutionary and genetic footprints of atmospheric tillandsioids tr...Read more -
Featured Publication – Integrative Identification by Hi-C Revealed Distinct Advanced Structural Variations in Lung Adenocarcinoma Tissue
The article published in Phenomics, titled “Integrative Identification by Hi-C Revealed Distinct Advanced Structural Variations in Lung Adenocarcinoma Tissue”. This study used high-throughput chromosome (Hi-C) conformation capture technology to detect the advanced structural variation...Read more -
Featured Publication – Ecological adaptation shaped the genetic structure of homoploid ferns against strong dispersal capacity
SLAF-seq has found notable applications! Today, let’s delve into a practical example of SLAF’s utilization in population evolutionary studies. In an article published in Molecular Ecology (IF = 6.185), titled “Ecological adaptation shaped the genetic structure of homoploid ferns...Read more -
Featured Publication – ippo Pathway Activation in Aged Mesenchymal Stem Cells Contributes to the Dysregulation of Hepatic Inflammation in Aged Mice
The article published in Advanced Science, Hippo Pathway Activation in Aged Mesenchymal Stem Cells Contributes to the Dysregulation of Hepatic Inflammation in Aged Mice. The mechanism of chronic inflammation in aging body is still obscure. In this study, immunosuppressive properties of aged MSCs ...Read more -
Featured Publication – Molecular and spatial signatures of human and rat corpus cavernosum physiopathological processes at single-cell resolution
Exciting News! In September 2024, our clients successfully published the first human and rat corpus cavernosum spatial transcriptomics map in the academic journal Cell Reports, titled “Molecular and spatial signatures of human and rat corpus cavernosum physiopathological processes at single...Read more -
Featured Publication – Metabolomic and metagenomic analyses of the Chinese mitten crab Eriocheir sinensis after challenge with Metschnikowia bicuspidata
The article published in Frontiers in Microbiology, Metabolomic and metagenomic analyses of the Chinese mitten crab Eriocheir sinensis after challenge with Metschnikowia bicuspidata, this study aimed to explore the changes in the metabolism and intestinal flora E. sinensis after 48 h of infection...Read more -
Featured Publication – Molecular and Spatial Signatures of Human and Rat Corpus Cavernosum Physiopathological Processes at Single-Cell Resolution
We are thrilled to announce that the research article titled “Molecular and Spatial Signatures of Human and Rat Corpus Cavernosum Physiopathological Processes at Single-Cell Resolution” by Dr. Zhao Liangyu’s team has been published in Cell Reports. This study employs single-cell...Read more -
Featured Publication – EXPLORING ROLES OF MIR-885-5P IN HEPATOCELLULAR CARCINOMA
The article published in Procedia of Multidisciplinary Research, EXPLORING ROLES OF MIR-885-5P IN HEPATOCELLULAR CARCINOMA. In this study, MicroRNAs (miRNAs) were found to play an important role in tumorigenesis, including in Hepatocellular carcinoma (HCC). Thus, this study compared the expressio...Read more -
Featured Publication – Chromosome-scale genome, together with transcriptome and metabolome, provides insights into the evolution and anthocyanin biosynthesis of Rubus rosaefolius Sm. (Rosaceae)
The rapid advancement of sequencing technology has led to the emergence of various omics fields, from DNA and RNA to trending metabolomics, each offering unique research systems. These omics are interconnected like a river: genomics at the upstream defines fundamental properties, while downstream...Read more -
Featured Publication – Acetyl-CoA metabolism maintains histone acetylation for syncytialization of human placental trophoblast stem cells
On July 30, 2024, One of our clients published a significant research finding in the international academic journal Cell Stem Cell. The research, titled “Acetyl-CoA metabolism maintains histone acetylation for syncytialization of human placental trophoblast stem cells,” investigated t...Read more -
Featured Publication – Aspergillus fumigatus hijacks human p11 to redirect fungal-containing phagosomes to non-degradative pathway
The decision whether endosomes enter the degradative or recycling pathway in mammalian cells is of fundamental importance for pathogen killing, and its malfunctioning has pathological consequences. The article, titled “Aspergillus fumigatus hijacks human p11 to redirect fungal-containing ph...Read more -
Featured Publication – Integration of ATAC-seq and RNA-seq Reveals the Dynamics of Chromatin Accessibility and Gene Expression in Zoysiagrass Response to Drought
Multi-omics application article: Integration of ATAC-seq and RNA-seq Reveals the Dynamics of Chromatin Accessibility and Gene Expression in Zoysiagrass Response to Drought. This article utilized an integrated multi-omics strategy, encompassing whole-genome sequencing (WGS), RNA sequencing (RNA-se...Read more
