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Featured Publication—Genetic linkage analysis of stable QTLs in Gossypium hirsutum RIL population revealed function of GhCesA4 in fiber development
Youlu Yuan and his team at the Chinese Academy of Agricultural Sciences (CAAS) Cotton Research Institute have successfully created a high-density genetic map using upland cotton’s recombinant inbred line (RIL) population. The team also identified crucial genes that are negatively correlate...Read more -
Featured Publication—Gut microbiota-derived metabolites facilitate melatonin’s neuroprotective properties in sleep deprivation-induced cognitive impairment
BMKGENE provided microbial amplicon sequencing and non-target metabolome testing services for this study “Gut microbiota-derived metabolites facilitate melatonin’s neuroprotective properties in sleep deprivation-induced cognitive impairment,” which delves into the findings of m...Read more -
Featured Publication—Targeting hnRNPC suppresses thyroid follicular epithelial cell apoptosis and necroptosis through m6A-modified ATF4 in autoimmune thyroid disease
The study published in Pharmacological Research titled “Targeting hnRNPC suppresses thyroid follicular epithelial cell apoptosis and necroptosis through m6A-modified ATF4 in autoimmune thyroid disease” utilized various sequencing techniques such as single-cell transcriptome, whole tr...Read more -
Featured Publication—Identification of a novel role for TL1A/DR3 deficiency in acute respiratory distress syndrome that exacerbates alveolar epithelial disruption
Acute Respiratory Distress Syndrome (ARDS) is an acute respiratory disease involving blood-gas barrier dysfunction. ARDS is primarily characterized by pulmonary edema caused by hyperpermeability of the vascular endothelium and alveolar epithelium. The article titled “Identification of a no...Read more -
Featured Publication—Mapping and functional dissection of the rumpless trait in Piao chicken identifies a causal loss of function mutation in the novel gene Rum
Another successful case of BMKGENE has been published online! On December 9, 2023, the article titled “Mapping and functional dissection of the rumpless trait in Piao chicken identifies a causal loss of function mutation in the novel gene Rum” was published in Molecular Biology and...Read more -
Featured Publication—Maternal vitamin B1 is a determinant for the fate of primordial follicle formation in offspring
BMKGENE provided sequencing and analysis services of 16S rDNA amplicon and metabolomics for the study titled “Maternal vitamin B1 is a determinant for the fate of primordial follicle formation in offspring”, which was published in Nature Communications. The study found that in mice,...Read more -
Featured Publication—Allele-defined genome reveals biallelic differentiation during cassava evolution
BMKGENE has extensive experience in this area, here is a featured publication for Cassava published on Molecular Plant. Haplotype analysis can provide a foundation for understanding the genetic mechanisms underlying important shape formations in a species. Most diploid genome assemblies ignore d...Read more -
Featured Publication—Different roles of host and habitat in determining the microbial communities of plant-feeding true bugs
BMKGENE provided full-length amplicon sequencing services for the study titled “Different roles of host and habitat in determining the microbial communities of plant-feeding true bugs” published in Microbiome. The study aimed to explore the symbiotic relationships between plant-feeding true bug...Read more -
Featured Publication—The nanoformula of zoledronic acid and calcium carbonate targets osteoclasts and reverses osteoporosis
BMKGENE provided long non-coding RNA sequencing services for the article “The nanoformula of zoledronic acid and calcium carbonate targets osteoclasts and reverses osteoporosis”, which was published in Biomaterials, herein, an OCs’ microenvironment-responsive nanoplatform-HMCZP is de...Read more -
Featured Publication—Comparative analysis of PacBio and ONT RNA sequencing methods for Nemopilema Nomurai venom identification
BMKGENE provided full-length transcriptome sequencing services using PacBio and ONT technologies for a study titled “Comparative analysis of PacBio and ONT RNA sequencing methods for Nemopilema Nomurai venom identification”, which was published in the journal Genomics. The study aimed...Read more -
BMKGENE Experience of WGBS&RNA-seq Joint Analysis
DNA methylation is one of the most extensively studied epigenetic modifications. It plays a crucial role in genome stability, gene transcription regulation, and trait development. The transcription of genes is determined by their methylation status, with low methylation levels associated with ge...Read more -
Featured Publication—Microbiome-metabolome analysis directed isolation of rhizobacteria capable of enhancing salt tolerance of Sea Rice 86
The article titled “Microbiome-metabolome analysis directed isolation of rhizobacteria capable of enhancing salt tolerance of Sea Rice 86” published in Science of the Total Environment explores the rhizosphere bacterial diversity and soil metabolome of SR86 seedlings under varying sa...Read more -
Featured Publication—Obese Ningxiang pig-derived microbiota rewires carnitine metabolism to promote muscle fatty acid deposition in lean DLY pigs
BMKGENE provided full-length 16s amplicon sequencing and metagenomics sequencing services for the article “Obese Ningxiang pig-derived microbiota rewires carnitine metabolism to promote muscle fatty acid deposition in lean DLY pigs”, which was published in The Innovation. This study aimed to unv...Read more
