The article published in Science China-Life Sciences, “Dynamic Changes in Butyrate Levels Regulate Satellite Cell Homeostasis by Preventing Spontaneous Activation During Aging“, is the first to report that the intestinal microbial community can regulate skeletal muscle satellite cell homeostasis and muscle function through the butyrate signaling pathway.
BMKGENE provided amplicon sequencing and metabolomics sequencing and analysis services for this study. Data from mice and population cohorts at different ages were analyzed in conjunction with multiple omics data, such as RNA-seq, 16S rRNA, and metabolomics. The findings of this study can provide new intervention targets and early warning schemes for the early prevention and intervention of skeletal muscle aging.
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Post time: Sep-08-2023