Evolutionary Genetics

Evolutionary genetic studies aim to understand the evolutionary trajectory of populations using polymorphism information in genomic sequences. The BMKCloud Evolutionary Genetics pipeline is designed to analyze WGS or Specific-Locus Amplified Fragment (SLAF) data from large populations. After quality control of the raw data, reads are aligned to the reference genome and variants are called. The pipeline includes phylogenetic tree construction, principal component analysis (PCA), population structure analysis, linkage disequilibrium (LD), selective sweep analysis, and candidate gene analysis.